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Similar Publications

HIGH RISK OF DIGESTIVE CANCERS IN PATIENTS WITH CELIAC DISEASE: A NATIONWIDE CASE CONTROL COHORT STUDY.

Clin Gastroenterol Hepatol

December 2024

Department of Clinical Investigation and Clinical Epidemiology, AP-HP-Centre-Université Paris Cité, Hôpital Européen Georges Pompidou, Paris, France; Department of Gastroenterology, AP-HP. Centre- Université Paris Cité, Hôpital Cochin, Paris, France. Electronic address:

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Extranodal marginal zone lymphoma (EMZL) is a rare subtype of non-Hodgkin's lymphoma characterized by the malignant transformation of lymphoid tissue at sites affected by chronic inflammation. Pleural marginal zone lymphoma (PMZL) is an infrequent manifestation of this condition. We report a case of PMZL co-occurring with primary lung adenocarcinoma.

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BTLA and HVEM: Emerging players in the tumor microenvironment and cancer progression.

Cytokine

October 2023

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Khalid University, Abha, Saudi Arabia.

Article Synopsis
  • Immunotherapy, especially immune checkpoint inhibitors (ICIs), is changing cancer treatment by targeting proteins that prevent the immune system from attacking cancer cells, with key examples being PD-1, PD-L1, and CTLA-4.
  • Further research has revealed another checkpoint mechanism involving BTLA and HVEM, which are linked to immune regulation and have been found overexpressed in several cancers like lung, ovarian, and glioblastoma.
  • The exploration of the BTLA/HVEM checkpoint is important for advancing immunotherapy options, aiming to enhance cancer treatment outcomes.
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Background: The coexistence of non-Hodgkin's lymphoma of the stomach and multiple primary lung adenocarcinomas with pulmonary cryptococcosis has rarely been reported.

Case Presentation: We herein present a 75-year-old man who was admitted to our hospital due to hematemesis. Gastroscopy and imaging revealed extensive stomach wall thickening and multiple lung lesions, including nodules and cavernous lesion.

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Article Synopsis
  • Metastatic bone disease (MBD) can lead to complications like pathological fractures, particularly in the pelvis, which significantly affect patients' mobility and quality of life.* -
  • Three cases of patients with pathological sacral fractures were treated using a new minimally invasive technique called SACRONAIL, resulting in immediate pain relief and improved mobility after surgery.* -
  • The study concludes that the SACRONAIL system is effective in treating pathological sacral fractures, allowing for full weight bearing and reducing the risk of complications, with all patients experiencing better pain management and mobility.*
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