and in Periodontitis in Adolescents and Young Adults.

Aim: This study aims to evaluate the association of and with periodontitis in adolescents and young adults in a Moroccan population.

Methods: 426 subjects aged between 12 and 25 years were recruited for the study. A pool of plaque sample was taken. Samples were cultured on Sabouraud Chloramphenicol medium at 37°C for 24-48 hours and then identified by the Vitek 2 YST system. Clinical data and presence of and were analyzed using Jamovi (Version 1.8).

Results: was observed in 25 subjects among 68 diseased patients (37%) and in 60 subjects among 358 healthy patients (17%). It can be reported that under normal yeast conditions, there is a statistically significant difference between these two groups ( < 0.001). was more prevalent in periodontitis than in healthy subjects (=0.026). Regarding clinical variables, subgroups of periodontitis subjects showed significant statistical differences for periodontal probing depth, clinical attachment loss, and number of decayed teeth in advanced periodontitis in comparison with initial or mild periodontitis. The results also indicate that the presence of the two species of is not related to gender or age ( > 0.05) nor related to the severity of the periodontal disease in this population.

Conclusion: Within the limits of our study, is more frequently associated with periodontitis. The potential role of in periodontitis pathogenesis is very complex. More studies on biofilm associated with different forms of periodontitis are necessary. It is also important to assess the coexistence of periodontitis and caries and the associated biofilms.