Interferon-alpha-16 (IFNA16) and tumor necrosis factor receptor superfamily member 19 (TNFRSF19) are cytokines that may play a role in adipogenesis and fatness. Single nucleotide polymorphisms (SNPs) of the porcine and genes were verified and their association with intramuscular fat (IMF) content and fatty acid (FA) composition were evaluated in commercial crossbred pigs. Two non-synonymous SNPs of the porcine c.413G > A and c.860G > C loci were detected in commercial crossbred pigs. The porcine c.413G >A polymorphism was significantly associated with stearic acid, total saturated FAs (SFAs), and the ratio of monounsaturated FAs (MUFAs) to SFAs ( < 0.05). Furthermore, the porcine c.860G > C polymorphism was found to be significantly associated with IMF content and arachidic acid levels ( < 0.05). The results revealed that porcine and polymorphisms are related to IMF content and/or FA composition and affirmed the importance of these cytokine genes as potential candidate genes for lipid deposition and FA composition in the muscle tissue of pigs.
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| http://dx.doi.org/10.3390/biology11010109 | DOI Listing |
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