Distinction between Antimicrobial Resistance and Putative Virulence Genes Characterization in Isolated from Different Sources.

Antibiotics (Basel)

Department of Clinical Laboratory Sciences, College of Applied Medical Sciences at Al-Quriat, Jouf University, Al-Quriat 77454, Saudi Arabia.

Published: January 2022

are gram-negative, thermotolerant, motile, and pleomorphic microorganisms that are only distantly related to those of the Enterobacteriaceae and Vibrionaceae families. One of the most common sources of contamination is human stool, but it may also be found in a wide range of other animals, plants, and aquatic habitats. Antimicrobial resistance in from seawater and shellfish was investigated, and pathogenicity involved genes were characterized as part of this study. Out of 384 samples of shellfish, 5.7% included . The presence of was also discovered in 5% of the seawater sampled. The antimicrobial resistance of 23 isolates derived from those samples was investigated. All isolates were sensitive to nalidixic acid, carbenicillin, cephalothin, erythromycin, kanamycin, tetracycline, and ciprofloxacin in the study. Several strains isolated from diseased shellfish were tested for virulence in shellfish by intraperitoneal injections. The LD values ranged from 12 × 10 to 3 × 10 cfu/shellfish. When looking for possible virulence factors that may play a significant role in bacterial infection in the current study, we found that all of these genes were present in these strains. These include genes such as elastase, lipase, flagellin, enterotoxin, and DNases. According to these findings, shellfish may serve as a reservoir for multi-resistant and help spread virulence genes across the environment.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8773300PMC
http://dx.doi.org/10.3390/antibiotics11010085DOI Listing

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