Management of Patients With Single-Ventricle Physiology Across the Lifespan: Contributions From Magnetic Resonance and Computed Tomography Imaging.

Can J Cardiol

Department of Diagnostic Imaging, Hospital for Sick Children, Toronto, Ontario, Canada; Joint Department of Medical Imaging, University Health Network, Toronto, Ontario, Canada; Peter Munk Cardiac Centre, University Health Network, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Published: July 2022

Cardiovascular magnetic resonance (CMR) and cardiac computed tomography (CCT) are robust cross-sectional imaging modalities that are increasingly being used to guide the diagnosis and management of those born with single-ventricle physiology. The purpose of this review is to acquaint the reader with the wide range of cross-sectional imaging applications that can be applied in this population. Illustrative examples of information provided by CMR and CCT are included, such as delineation of cardiac anatomy, measurement of ventricular volumetry, interrogation of vascular anatomy and flows, evaluation of myocardial viability, and exclusion of thromboembolic disease. Focus is placed on the appropriate selection and timing of advanced cardiac imaging modalities, and differentiations are made between established indications for imaging and emerging applications (such as 4-dimensional [4D] flow assessment and parametric imaging for identification of diffuse fibrosis using CMR). Potential CMR and CCT contributions in the selection of interventional strategies in the child and for surveillance of postoperative complications in the adult are highlighted. Furthermore, the importance of extracardiac cross-sectional imaging in the single-ventricle population is emphasized given the recognition that complications post-Fontan palliation are not limited to the cardiovascular system but will often include extracardiac manifestations of disease (such as hepatic disease or lymphatic abnormalities), While the value of CMR and CCT for contemporary clinical care of individuals born with single-ventricle physiology appears to be well-established, further research will be necessary to explore the impact of risk stratification using imaging biomarkers on clinical outcomes following Fontan palliation.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cjca.2022.01.011DOI Listing

Publication Analysis

Top Keywords

single-ventricle physiology
12
cross-sectional imaging
12
cmr cct
12
magnetic resonance
8
computed tomography
8
imaging
8
imaging modalities
8
born single-ventricle
8
cmr
5
management patients
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!