AI Article Synopsis
- Uveal melanoma is the most common eye cancer in adults, often affecting the choroid and ciliary body, with rare instances (2-3%) involving the iris.
- A 56-year-old patient presented with ongoing inflammatory glaucoma in one eye for 6 years, leading to suspicion of iris melanoma due to changes in iris color and thickness.
- Despite an inconclusive biopsy, the condition worsened, resulting in the removal of the eye, which revealed a diagnosis of iridociliary melanoma with a specific growth pattern upon further examination.
Article Abstract
Uveal melanoma is the most common primary malignancy of the eye in adults. It may involve the choroid and ciliary body, and in only 2-3% of cases it involves the iris. We present a case of a 56-year-old patient with a 6-year history of unilateral, inflammatory, refractory glaucoma of the right eye. Due to acquired heterochromia and heterogeneous thickness of the iris, iris melanoma was suspected, but the incisional biopsy did not confirm the diagnosis. In the next months, the lesion enlarged and the eye globe was enucleated. Histopathological examination revealed an iridociliary melanoma with annular growth pattern.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.5114/pjp.2021.111777 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Unlabelled: Considering the similarity in clinical presentations of iris neoplasms of various origins, questions of their noninvasive diagnosis remain relevant. Optical coherence tomography angiography (OCT-A) is one of the imaging method that enables visualization of tumor vessels.
Purpose: This article examines the features of angioarchitecture, vascular network density, and perfusion density of iris melanoma and progressive iris nevus using OCT-A.
Oculodermal melanocytosis in Asian Indian patients: Prevalence, clinical presentation, and association with choroidal melanoma.
Indian J Ophthalmol
January 2025
The Operation Eyesight Universal Institute for Eye Cancer, L V Prasad Eye Institute, Hyderabad, Telangana, India.
Objective: To study the prevalence, clinical presentation, treatment, and follow-up of ocular (dermal) melanocytosis (ODM) and its association with choroidal melanoma (CM) in Asian Indian patients.
Methods: This was a retrospective case series of patients with ODM conducted in a quaternary eye care center.
Results: Of the total 1.
Geographical disparities in cancer and occupational exposure to pesticides in a French-West Indies territory (2006-2019).
BMC Cancer
December 2024
University Hospital of Martinique, Oncology Hematology Urology Department, General Cancer Registry of Martinique, Fort-de-France, Martinique.
Article Synopsis
- A new study in the French West Indies examines the connection between chlordecone pesticide soil contamination and cancer rates in Martinique from 2006 to 2019, using a more sensitive contamination indicator.
- This study analyzed data from 23,218 cancer cases, finding that women exposed to higher soil contamination levels showed an increased risk for several cancers, including lung and thyroid cancer, while no significant correlation was observed for breast or prostate cancer.
- The findings suggest that women in Martinique are disproportionately affected by chlordecone exposure, highlighting the need for ongoing research into the environmental impacts of pesticides on public health.
Diffuse iris melanoma leading to secondary glaucoma in a lion (Panthera leo)-A case report.
Vet Ophthalmol
December 2024
Departamento de Medicina Veterinária, Universidade Federal do Paraná (UFPR), Curitiba, Brazil.
Article Synopsis
- - A 12-year-old male African lion was diagnosed with eye issues, including discharge and swelling, leading to the discovery of an intraocular mass via ocular ultrasonography.
- - The lion underwent enucleation (removal of the eye), and histopathological analysis confirmed the presence of diffuse iris melanoma, a type of cancer affecting the iris and ciliary body.
- - While diffuse iris melanoma is common in domestic cats, it's rarely seen in larger felids like lions, and more research is needed to understand its impact and prognosis in these animals.
Clinical features of midzonal iris pigment epithelial cysts: surprising findings revealed by ultrasound biomicroscopy.
Graefes Arch Clin Exp Ophthalmol
November 2024
Department of Ophthalmology, University of Cincinnati College of Medicine, Cincinnati, OH, 45267-0527, USA.
Article Synopsis
- The study examined midzonal iris pigment epithelial (IPE) cysts, which are usually harmless but can be confused with ciliary body melanoma, to better understand their characteristics using ultrasound biomicroscopy (UBM).
- Researchers reviewed 69 patient charts, finding that cysts were most common in older adults (median age 66), with a slight female majority and various cyst sizes, often located inferotemporally in the eye.
- UBM revealed that many cases thought to have multiple cysts were actually single cysts with distinct shapes, and associated peripheral IPE cysts were found in a majority of the evaluated eyes.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!