Valence of animal pheromone blends can vary due to differences in relative abundance of individual components. For example, in , whether a pheromone blend is perceived as "male" or "hermaphrodite" is determined by the ratio of concentrations of ascr#10 and ascr#3. The neuronal mechanisms that evaluate this ratio are not currently understood. We present data that suggest that the function of guanylyl cyclase ODR-1 in AWB neurons is required for the effect of ascr#3 that counteracts the activity of ascr#10. This finding defines a new module in the neuronal mechanism that determines the sexual identity of pheromone.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8758999 | PMC |
| http://dx.doi.org/10.17912/micropub.biology.000507 | DOI Listing |
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