Treatment for late-stage cancer patients should be discussed depending on the patients' will, however it is not sometimes fully discussed in our daily practice. Based on this background, the information-sharing tool for metastatic colorectal cancer patients, who are refractory to first-line and second-line chemotherapy and/or who are given a year to live, has been introduced in our university hospital since November 2019. To evaluate the utility of this tool, the influence of the tools on the outcome of the patients was evaluated. Regarding the comparison between the patients before and after the introduction of the information-sharing tool, the period between the day of the consent to the DNAR between the day of the death is longer in the patients after the introduction than those before the introduction(median 43 vs 6 days, p=0.025). The introduction of the information-sharing tool can provide the metastatic colorectal cancer patients with more opportunities to discuss how to spend the rest of their lives and with longer time at the place where they want to stay.
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PLoS One
January 2025
Academy for Health Equity, Prevention and Wellbeing (AHEPW) School of Health Sciences, Bangor University, Gwynedd, United Kingdom.
Background And Objective: Personal wheelchair budgets (PWBs) are offered to everyone in England eligible for a wheelchair provided through the National Health Service (NHS) to support their choice of equipment. The WATCh (Wheelchair outcomes Assessment Tool for Children) and related WATCh-Ad for adults are patient-centred outcome measures (PCOMs) developed to help individual users express their main outcome needs when obtaining a wheelchair and rate their satisfaction with subsequent outcomes after receiving their equipment. Use was explored in a real-world setting, aiming to produce guidance for use alongside the PWB process.
View Article and Find Full Text PDFGigascience
January 2025
INRAE, Université de Bordeaux, F-33610 Cestas, France.
Background: Descriptive metadata are vital for reporting, discovering, leveraging, and mobilizing research datasets. However, resolving metadata issues as part of a data management plan can be complex for data producers. To organize and document data, various descriptive metadata must be created.
View Article and Find Full Text PDFSci Rep
January 2025
The Army Engineering University of PLA, Nanjing, 211117, Jiangsu, China.
The rapid proliferation of mobile social networks has significantly accelerated the dissemination of misinformation, posing serious risks to social stability, public health, and democratic processes. Early detection of misinformation is essential yet challenging, particularly in contexts where initial content propagation lacks user feedback and engagement data. This study presents a novel hybrid model that combines Bidirectional Encoder Representations from Transformers (BERT) with Long Short-Term Memory (LSTM) networks to enhance the detection of misinformation using only textual content.
View Article and Find Full Text PDFBMJ Open
January 2025
Department of Rehabilitation and Sports Medicine, Hannover Medical School, Hannover, Germany.
Introduction: The United Nations underlines the participation in all domains of daily living for people with intellectual and/or multiple disabilities in the Disability Rights Convention, which also includes medical services. In line with this, the German Federal Participation Act has further developed the relevant disability policy at the national level. This also implies access to comprehensive medical care.
View Article and Find Full Text PDFBMJ Open
January 2025
Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK
Introduction: Heart failure (HF) is a complex clinical syndrome. Accurate risk stratification and early diagnosis of HF are challenging as its signs and symptoms are non-specific. We propose to address this global challenge by developing the STRATIFYHF artificial intelligence-driven decision support system (DSS), which uses novel analytical methods in determining the risk, diagnosis and prognosis of HF.
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