The purpose of this investigation was to analyze the performance of magnetite graphene oxide modified with β-cyclodextrin (GO@FeO@β-CD) for adsorption of methotrexate (MTX) and doxorubicin (DOX) from aqueous solutions. Characterization of GO@FeO@β-CD was carried out using some methods. The perfect conditions for the adsorption of MTX and DOX were 7.0, 45 min, 20 mg, and 25 °C for solution pH, contact time, adsorbent dose, and temperature, respectively, with removal efficiency values of 97.8% and 98.5% for MTX and DOX, respectively. The adsorption kinetic of MTX and DOX via GO@FeO@β-CD followed pseudo second-order (PSO) model, while the adsorption isotherm obeyed Langmuir model by monolayer adsorption with maximum adsorption capacities of 198.5 and 204.5 mg g for MTX and DOX, respectively. Therefore, it could be argued that HCl and 0.1 mol L NaOH would reflect adequate elution properties for GO@FeO@β-CD recovery.
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