Polydiacetylenes (PDAs) are a family of mechanochromic polymers that change color from blue to red and emit fluorescence when exposed to external stimuli, making them extremely popular materials in biosensing. Although several informative reviews on PDA biosensing have been reported in the last few years, their mechanochromism, where external forces induce the color transition, has not been reviewed for a long time. This mini review summarizes recent progress in PDA mechanochromism, with a special focus on the quantitative and nanoscopic data that have emerged in recent years.
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Targeted Computed Tomography Visualization and Healing of Inflammatory Bowel Disease by Orally Delivered Bacterial-Flagella-Inspired Polydiiododiacetylene Nanofibers.
ACS Nano
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National Engineering Research Center for Nanomedicine, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan 430074, China.
Accurate diagnosis and timely therapeutic intervention of inflammatory bowel disease (IBD) is essential in preventing the progression of the disease, although it still represents an insurmountable challenge. Here we report the design of bacterial-flagella-inspired polydiiododiacetylene (PIDA) nanofibers and its performance in targeted computed tomography (CT) imaging and on-demand therapeutic intervention of IBD. With a morphology mimicking bacterial flagella, PIDA nanofibers attach on the mucus layer of the gastrointestinal (GI) tract after oral administration, evenly distributing on the GI surface to portray the GI lining under CT scan within 2 h.
View Article and Find Full Text PDFRecent progress in polydiacetylene mechanochromism.
Nanoscale
February 2022
Institute of Industrial Science, The University of Tokyo, 4-6-1 Komaba Meguro-Ku, Tokyo 153-8505, Japan.
Polydiacetylenes (PDAs) are a family of mechanochromic polymers that change color from blue to red and emit fluorescence when exposed to external stimuli, making them extremely popular materials in biosensing. Although several informative reviews on PDA biosensing have been reported in the last few years, their mechanochromism, where external forces induce the color transition, has not been reviewed for a long time. This mini review summarizes recent progress in PDA mechanochromism, with a special focus on the quantitative and nanoscopic data that have emerged in recent years.
View Article and Find Full Text PDFTopochemical Polymerization of a Diacetylene in a Chalcogen-Bonded (ChB) Assembly.
Angew Chem Int Ed Engl
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Univ Rennes, CNRS, ISCR (Institut des Sciences Chimiques de Rennes) UMR 6226, 35042, Rennes, France.
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View Article and Find Full Text PDFFirst principles modeling of exciton-polaritons in polydiacetylene chains.
J Chem Phys
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Laboratory for Chemistry of Novel Materials, University of Mons, Place du Parc, 20, B-7000 Mons, Belgium.
Exciton-polaritons in organic materials are hybrid states that result from the strong interaction of photons and the bound excitons that these materials host. Organic polaritons hold great interest for optoelectronic applications; however, progress toward this end has been impeded by the lack of a first principles approach that quantifies light-matter interactions in these systems, which would allow the formulation of molecular design rules. Here, we present a theoretical framework that combines first principles calculations for excitons with classical electrodynamics in order to quantify light-matter interactions.
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