Background: Until recently, combined heart-liver-kidney transplantation was considered too complex or too high-risk an option for patients with end-stage heart failure who present with advanced liver and kidney failure as well.
Aims: The objective of this paper is to present our institution's best practices for successfully executing this highly challenging operation. At our institution, referral patterns are most often initiated through the cardiac team.
Results: Determinants of successful outcomes include diligent multidisciplinary patient selection, detailed perioperative planning, and choreographed care transition and coordination among all transplant teams. The surgery proceeds in three distinct phases with three different teams, linked seamlessly in planned handoffs. The selection and perioperative care are executed with determined collaboration of all of the invested care teams.
Conclusions: Combined heart-liver-kidney transplantation can be successfully done by careful selection, coordination, and execution.
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http://dx.doi.org/10.1111/ctr.14586 | DOI Listing |
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2024
Department of Blood Transfusion, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200127, China.
Objective: To investigate and assess hemolytic transfusion reaction in patient with complex and combined anti-Fy and anti-Jk which so as to provide a safety blood transfusion strategy.
Methods: ABO/Rh blood grouping, antibody screening and identification, and Coombs' tests were performed by the routine serological methods include manual tube and automatic blood group analyzer with matching micro-column gel cards from Diagnostic Grifols and Jiangsu LIBO. The hospital information system and laboratory information system were used to collect dada on patients' blood routine tests, liver and kidney function, coagulation, cardiac function, and other clinical indicators before and after blood transfusion were analyzed and compared in conjunction with the patients' clinical manifestations.
Zhongguo Zhong Yao Za Zhi
September 2024
School of Pharmaceutical Sciences, Guizhou Medical University Guiyang 550004, China Engineering Research Center for the Development and Application of Ethnic Medicine and TCM(Ministry of Education), National Engineering Research Center of Miao's Medicine, Guizhou Medical University Guiyang 550004, China.
Shock
August 2024
State Key Laboratory of Trauma, Burns and Combined Injury, Shock and Transfusion Department, Da ping Hospital, Army Medical University, Chongqing400042, China.
Aim: To elucidate whether the application of the mitochondrial division inhibitor Mdivi-1 can protect organ function and prolong the treatment window for traumatic hemorrhagic shock.
Methods: Before definitive haemostasis treatment, Mdivi-1 (0.25 mg/kg, 0.
Cancers (Basel)
August 2023
Department of Radiation Oncology, University of California Los Angeles, Los Angeles, CA 90095, USA.
Anal Chem
June 2023
Key Laboratory of Mass Spectrometry Imaging and Metabolomics (Minzu University of China), National Ethnic Affairs Commission, Beijing 100081, P. R. China.
Zebrafish () represent an effective model biological material for human disease research, even for personalized precision medicine. Thus, it is necessary to fully characterize their molecular information in order to obtain a global metabolic profile. Here, a spatially resolved metabolomics method for whole-body zebrafish analysis was established based on an air-flow-assisted desorption electrospray ionization-mass spectrometry imaging (AFADESI-MSI) system.
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