AI Article Synopsis
- Two new BODIPY-based fluorescent rotors were developed to react sensitively to viscosity changes in living cells, showing a fluorescence "turn-on" effect.
- The increase in fluorescence is due to the restricted rotation of the -CF group in thicker environments.
- One of the probes, which includes a positively charged group, demonstrates effective targeting of mitochondria and exhibits an Aggregation-Induced Emission (AIE) property.
Article Abstract
Two novel -CF BODIPY-based fluorescent rotors have been rationally prepared and found to sensitively respond to viscosity in living cells with a fluorescence "turn-on" effect, attributed to the special restricted rotation of -CF group in viscous environments. Interestingly, a monostyryl probe with one cationic group exhibits good mitochondrial localization and AIE property.
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| http://dx.doi.org/10.1039/d1cc06532g | DOI Listing |
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