AI Article Synopsis

Article Abstract

The foremost common natural polymers are carbohydrate-based polymers or polysaccharides, having a long chain of monosaccharide or disaccharide units linked together via glycosidic linkage to form a complex structure. There are several uses of carbohydrate-based polymers in the biomedical sector due to their attractive features, including less toxicity, biocompatibility, biodegradability, high reactivity, availability, and relative inexpensiveness. The aim of our study was to explore the synthetic approaches for the preparation of numerous carbohydrate-based polyurethanes (PUs) and their wide range of pharmaceutical and biomedical applications. The data summarized in this study show that the addition of carbohydrates in the structural skeleton of PUs not only improves their suitability but also affects their applicability for use in biological applications. Carbohydrate- based units are incorporated into the PUs, which is the most convenient method for the synthesis of novel biocompatible and biodegradable carbohydrate-based PUs for use in various biomedical applications.

Download full-text PDF

Source
http://dx.doi.org/10.2174/1573412918666220118113546DOI Listing

Publication Analysis

Top Keywords

biomedical applications
12
carbohydrate-based polymers
8
carbohydrate-based
5
biomedical
4
applications carbohydrate-based
4
carbohydrate-based polyurethane
4
polyurethane biosynthesis
4
biosynthesis degradation
4
degradation foremost
4
foremost common
4

Similar Publications

The "similarity of dissimilarities" is an emerging paradigm in biomedical science with significant implications for protein function prediction, machine learning (ML), and personalized medicine. In protein function prediction, recognizing dissimilarities alongside similarities provides a more detailed understanding of evolutionary processes, allowing for a deeper exploration of regions that influence biological functionality. For ML models, incorporating dissimilarity measures helps avoid misleading results caused by highly correlated or similar data, addressing confounding issues like the Doppelgänger Effect.

View Article and Find Full Text PDF

Protocol for oral fecal gavage to reshape the gut microbiota in mice.

STAR Protoc

January 2025

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital, Linkou, Taoyuan, Taiwan; Grandulate Institute of Biomedical Science, College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Fecal microbiota transplantation (FMT) is clinically applied, while oral FMT (oral fecal gavage [OFG]) is preferred for experimental mice. Here, we present a protocol for OFG in antibiotic-pretreated mice, demonstrating the progressive, time-dependent evolution of the gut microbiota in the recipients. We describe steps for fecal sample collection and preparation procedures, oral gavage, and monitoring gut microbiota changes.

View Article and Find Full Text PDF

Purpose: The integration of artificial intelligence (AI), particularly deep learning (DL), with optical coherence tomography (OCT) offers significant opportunities in the diagnosis and management of glaucoma. This article explores the application of various DL models in enhancing OCT capabilities and addresses the challenges associated with their clinical implementation.

Methods: A review of articles utilizing DL models was conducted, including convolutional neural networks (CNNs), recurrent neural networks (RNNs), generative adversarial networks (GANs), autoencoders, and large language models (LLMs).

View Article and Find Full Text PDF

Solution Blow Spinning: An Emerging Nanomaterials-Based Wound-Care Technology.

J Biomed Mater Res B Appl Biomater

February 2025

Department of Bioengineering, Clemson University, Clemson, South Carolina, USA.

Application of one-dimensional nanofibers have witnessed exponential growth over the past few decades and are still emerging with their excellent physicochemical and electrical properties. The driving force behind this intriguing transition lies in their unique high surface-to-volume ratio, ubiquitous nanodomains, improved tensile strength, and flexibility to incorporate deliberate functionalities required for specific and advanced applications. Besides numerous benefits, nanomaterials may adversely interact with biological tissues and potentially be cytotoxic and carcinogenic.

View Article and Find Full Text PDF

A CRISPR-Cas and Argonaute-Driven Two-Factor Authentication Strategy for Information Security.

ACS Nano

January 2025

Department of Clinical Laboratory of Sir Run Run Shaw Hospital, College of Biosystems Engineering and Food Science, Zhejiang University School of Medicine, Hangzhou 310058, People's Republic of China.

The escalating growth in computing power and the advent of quantum computing present a critical threat to the security of modern cryptography. Two-factor authentication strategies can effectively resist brute-force attacks to improve the security of access control. Herein, we proposed a two-factor and two-authentication entity strategy based on the trans-cleavage activity of CRISPR-Cas and the "dual-step" sequence-specific cleavage of Argonaute.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!