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Tunneled Pleural Catheters: An Effective Nonsurgical Alternative for Nonexpandable Lung in Chronic Pleural Infection.
J Bronchology Interv Pulmonol
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Division of Thoracic Surgery and Interventional Pulmonology, Beth Israel Deaconess Medical Center, Harvard Medical School.
Background: Open window thoracostomy (OTW) is the standard of care for debilitated patients with chronic pleural infection and nonexpandable lungs (NEL) who are not candidates for major surgical intervention. Tunneled pleural catheters (TPC) offer tremendous treatment potential in this setting based on their efficacy in malignant pleural effusion and NEL. We aim to assess the efficacy, safety, and health care utilization of TPC in this setting.
View Article and Find Full Text PDFTreatment-Emergent Major Adverse Cardiovascular and Thromboembolic Events were Infrequent During Clinical Trials of Pegloticase.
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Amgen Inc, Thousand Oaks, CA, USA.
Objectives: Long-term maintenance of serum urate (SU) levels <6 mg/dl reduces gout flare frequency. However, urate-lowering therapy (ULT) initiation can induce gout flare. The incidence of thromboembolic (TE) and cardiovascular (CV) events has been shown to increase in the 30 and 120 days following gout flare, respectively; therefore, the question of ULT initiation increasing patient risk for CV/TE events has been raised.
View Article and Find Full Text PDFThe Impact of Cloaking Digital Footprints on User Privacy and Personalization.
Big Data
January 2025
Department of Engineering Management, University of Antwerp, Antwerp, Belgium.
Our online lives generate a wealth of behavioral records--which are stored and leveraged by technology platforms. These data can be used to create value for users by personalizing services. At the same time, however, it also poses a threat to people's privacy by offering a highly intimate window into their private traits (e.
View Article and Find Full Text PDFFrom Knowledge to Practice: Design, Implementation, and Evaluation of an Evidence-Based Educational Module to Increase Cultural Awareness in Nursing Students.
Creat Nurs
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Society and Ageing Research Lab, Vrije Universiteit Brussel (VUB), Brussels, Belgium.
Educational programs for health-care providers increasingly implement culturally sensitive care. Clear methods for educating students in cultural awareness are still lacking. Research indicates that simply increasing knowledge on ethnicity, culture, or migration does not improve culturally sensitive behavior and can foster stereotypes.
View Article and Find Full Text PDFEnhancement of Interferon-γ Secretion by Extract Supplementation After Exhaustive Endurance Exercise in Healthy Men: A Double-blind, Placebo-controlled Trial.
Int J Med Sci
January 2025
Center for General Education, Taipei Medical University, Taipei 110301, Taiwan.
To investigate the effects of 12-week extract supplementation on immune responses and inflammatory cytokines after exhaustive endurance exercise (EEE), emphasizing its novel focus on peripheral blood mononuclear cells (PBMCs) cytokine secretion and the implications of interferon-γ (IFN-γ) as a marker for immune modulation. Twenty healthy men were recruited and assigned into maca and placebo groups using a matched-pair design based on their maximal oxygen consumption (V̇O). All participants consumed 2.
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