Minor terpenoids from the stems and twigs of .

J Asian Nat Prod Res

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Published: May 2022

Four minor undescribed terpenoids, including a monoterpenoid () and three triterpenoids (, and ), together with 26 known terpenoids were isolated from the stems and twigs of . Their structures were identified by extensive spectroscopic analyses and electronic circular dichroism (ECD) techniques. Compound showed excellent cytotoxicity against human colon cancer cell (HCT-116) with IC value of 2.56 μM. Compounds and exhibited partly inhibitory effects on nitric oxide production stimulated by lipopolysaccharide-induced neuroinflammation in microglia cells at 10 μM with inhibition ratios of 39.70% and 28.08%, respectively.

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Source
http://dx.doi.org/10.1080/10286020.2022.2027916DOI Listing

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