AI Article Synopsis
- A recent study by Wang et al. explores the role of the RNA-binding protein IMP2 in macrophage activation, highlighting its regulatory differences in humans and mice.
- The research indicates that while IMP2 expression aligns in anti-inflammatory macrophages for both species, the regulation diverges in inflammatory macrophages.
- These findings provide new insights into how macrophage responses differ across species, which could impact future research and therapeutic approaches.
Article Abstract
Recently, first insights into the regulation and the role of the RNA-binding protein IMP2 in macrophage activation have been published by Wang et al. This study addresses differences in the regulation of IMP2 between the human and murine system. While the expression of IMP2 in anti-inflammatory macrophages is synchronous in mice and men, IMP2 expression is regulated differently in inflammatory macrophages.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8922093 | PMC |
| http://dx.doi.org/10.1002/advs.202104372 | DOI Listing |
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