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Background: Alzheimer's Disease (AD) is characterized by progressive impairment of cognition and memory, including the loss of episodic memory. The use of non-invasive brain stimulation therapies to modulate memory encoding processes is a promising avenue for potential treatment. Previous studies have shown that the use of Transcranial Magnetic Stimulation (TMS) applied to lateral parietal cortex can improve memory in older adults who have received a diagnosis of Mild Cognitive Impairment.
View Article and Find Full Text PDF[Therapeutic targets of adolescent depression with attenuated symptoms of schizophrenia].
Zh Nevrol Psikhiatr Im S S Korsakova
December 2024
Mental Health Research Centre, Moscow, Russia.
Objective: Identification of therapeutic targets in the treatment of adolescent depression with attenuated symptoms of schizophrenia and assessment of the effectiveness of therapeutic interventions.
Material And Methods: One hundred and twenty-three patients (mean age 19.6±2.
Evaluating semantic control with transcranial magnetic stimulation: a systematic review with meta-analysis.
Front Psychol
December 2024
Department of Developmental and Social Psychology, University of Padova, Padova, Italy.
Background: This meta-analysis investigates the role of specific brain regions in semantic control processes using Transcranial Magnetic Stimulation (TMS). According to the Controlled Semantic Cognition framework, control processes help manage the contextually appropriate retrieval of semantic information by activating a distributed neural network, including the inferior frontal gyrus, the posterior middle temporal gyrus, and inferior parietal lobule. Lesions in these areas can lead to difficulties in manipulating weakly activated or competing semantic information.
View Article and Find Full Text PDFAccurate determination of motor evoked potential amplitude in TMS: The impact of personal and experimental factors.
Clin Neurophysiol
December 2024
REVAL - Rehabilitation Research Center, Faculty of Rehabilitation Sciences, University of Hasselt, Diepenbeek, Belgium.
Objective: Corticospinal excitability can be quantified using motor-evoked potentials (MEP) following transcranial magnetic stimulation (TMS). However, the inherent variability of MEPs poses significant challenges. We establish a framework using personal and experimental factors to select the optimal number of trials (n) required for reliable MEP estimates.
View Article and Find Full Text PDFTMS-evoked potential propagation reflects effective brain connectivity.
J Neural Eng
December 2024
Biomedical Sciences and Biomedical Engineering Division, School of Biological Sciences, University of Reading, Reading, United Kingdom.
Cognition is achieved through communication between brain regions. Consequently, there is considerable interest in measuring effective connectivity. A promising effective connectivity metric is transcranial magnetic stimulation (TMS) evoked potentials (TEPs), an inflection in amplitude of the electroencephalogram recorded from one brain region as a result of TMS applied to another region.
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