Breast cancer is one of the leading causes of death in women worldwide-the rapid increase in breast cancer has brought about more accessible diagnosis resources. The ultrasonic breast cancer modality for diagnosis is relatively cost-effective and valuable. Lesion isolation in ultrasonic images is a challenging task due to its robustness and intensity similarity. Accurate detection of breast lesions using ultrasonic breast cancer images can reduce death rates. In this research, a quantization-assisted U-Net approach for segmentation of breast lesions is proposed. It contains two step for segmentation: (1) U-Net and (2) quantization. The quantization assists to U-Net-based segmentation in order to isolate exact lesion areas from sonography images. The Independent Component Analysis (ICA) method then uses the isolated lesions to extract features and are then fused with deep automatic features. Public ultrasonic-modality-based datasets such as the Breast Ultrasound Images Dataset (BUSI) and the Open Access Database of Raw Ultrasonic Signals (OASBUD) are used for evaluation comparison. The OASBUD data extracted the same features. However, classification was done after feature regularization using the lasso method. The obtained results allow us to propose a computer-aided design (CAD) system for breast cancer identification using ultrasonic modalities.
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http://dx.doi.org/10.7717/peerj-cs.805 | DOI Listing |
Cancer Cell Int
December 2024
Department of Ultrasound, Chongqing General Hospital, Chongqing University, Chongqing, 401147, China.
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MKA Breast Cancer Clinic, Tepe Prime, Ankara, Turkey. Electronic address:
Trends Mol Med
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Cancer Signaling and Microenvironment Program, Fox Chase Cancer Center, Philadelphia, PA, USA. Electronic address:
Genetic and epigenetic defects of the p53 system have previously been associated with resistance to CDK4/6 inhibitors in women with HR breast cancer. Recent data from Kudo et al. demonstrate that CDK2-targeting agents may offer an effective strategy to circumvent such resistance by enforcing cellular senescence downstream of RBL2 dephosphorylation.
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Breast Cancer Center, Zhejiang Cancer Hospital, Hangzhou Institute of Medicine (HIM), Chinese Academy of Sciences, Hangzhou, Zhejiang 310022, China. Electronic address:
Am J Pathol
December 2024
Department of Computer Science, Faculty of Engineering Sciences, University College London, Gower Street, London, WC1E 6BT, United Kingdom.
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