Background: Compensation after living donor nephrectomy is well known, and a compensation prediction score (CPS) was made in Japan previously. The aim of this study was to perform external validation of CPS in the United States.
Methods: We studied retrospectively 78 living donor nephrectomies in our institution. We defined a favorable compensation as a postdonation estimated glomerular filtration rate (eGFR) at 1 year of >60% of the predonation eGFR. We analyzed the living donors' clinical characteristics and outcomes and validated CPS score.
Results: The median (range) donor age was 43 (21-63) years, and median body mass index was 26.9 (18.3-35.9) kg/m. Forty-four percent of donors were White. The donor predonation eGFR was 105 (61-134) mL/min/1.73 m, and the postdonation eGFR at 1 year was 73.2 (0-115) mL/min/1.73 m. Eighty-three percent of donors had a favorable compensation. The CPS was 9.6 (1.6-15.6) and showed strong diagnostic accuracy for predicting favorable compensation (area under the curve, 0.788; 95% confidence interval, 0.652-0.924; P = .001). The CPS showed a significant positive correlation with the postdonation eGFR at 1 year (R = 0.54; P < .001).
Conclusions: In the United States, the CPS would be a valid tool with which to predict a favorable compensation of remnant kidney function.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.transproceed.2021.08.067 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Sensitivity of pteropod calcification to multi stressor variability in coastal habitats.
Mar Environ Res
December 2024
School of Oceanography, University of Washington, 1492 NE Boat St., Seattle, WA, 98105, USA; Applied Physics Laboratory, University of Washington, Box 355640, Seattle, WA, 98105, USA.
Comprehensive understanding of environmental multiple stressors on calcification in marine calcifiers remains an important topic of study, especially under ocean global change associated with multiple stressors. We explore the impact of multiple stressor on pteropod calcification in the southern Salish Sea (Washington, U.S.
View Article and Find Full Text PDFSeizures and status epilepticus in anti-NMDA receptor encephalitis.
J Neurol
January 2025
Department of Neurology, Mayo Clinic, Rochester, MN, 55905, USA.
Background: Seizures, including status epilepticus (SE), are common in anti-NMDA receptor encephalitis (NMDARE). We aimed to describe clinical and electrographic features of patients with seizures with NMDARE, determine factors associated with SE, and describe long-term seizure outcomes.
Methods: We retrospectively identified patients with seizures in the setting of NMDARE treated at inpatient Mayo Clinic sites during the acute phase of encephalitis between October 2008 and March 2023.
Incidence rate of total knee arthroplasties in eleven European countries: Do they reach a plateau?
PLoS One
January 2025
Université de Brest, UBO, LATIM, UMR 1101, Brest, France.
Background: From several decades, the evolutions of the Incidence Rate (IR) of Primary Knee Arthroplasties are continuously increasing worldwide and have been widely studied in several countries. Some recent works have highlighted the fact that the IR is following a sigmoid curve composed of an exponential growth followed by a linear phase and finished by a plateau. Our objective is to assess the IR evolution of eleven European countries, representing thus a large proportion of this continent, regarding this sigmoid.
View Article and Find Full Text PDFDissolution Thermodynamics of the Solubility of Sulfamethazine in (Acetonitrile + 1-Propanol) Mixtures.
Pharmaceuticals (Basel)
November 2024
Grupo de Investigaciones Farmacéutico-Fisicoquímicas, Departamento de Farmacia, Facultad de Ciencias, Universidad Nacional de Colombia, Sede Bogotá, Carrera 30 No. 45-03, Bogotá 110321, Cundinamarca, Colombia.
: Solubility is one of the most important parameters in the research and development processes of the pharmaceutical industry. In this context, cosolubility is one of the most used strategies to improve the solubility of poorly soluble drugs, besides allowing to identify some factors involved in the dissolution process. The aim of this research is to evaluate the solubility of sulfamethazine in acetotinitrile + 1-propanol cosolvent mixtures at 9 temperatures (278.
View Article and Find Full Text PDFHierarchical architecture of neo-sex chromosomes and accelerated adaptive evolution in tortricid moths.
Genome Res
January 2025
Institute of Plant Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing 100097, China;
Sex chromosomes can expand through fusion with autosomes, thereby acquiring unique evolutionary patterns. In butterflies and moths (Lepidoptera), these sex chromosome-autosome (SA) fusions occur relatively frequently, suggesting possible evolutionary advantages. Here, we investigated how SA fusion affects chromosome features and molecular evolution in leafroller moths (Lepidoptera: Tortricidae).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!