We observe a wealth of multimagnon bound states in the strongly anisotropic spin-1 triangular antiferromagnet FeI_{2} using time-domain terahertz spectroscopy. These unconventional excitations can arise in ordered magnets due to attractive magnon-magnon interactions and alter their properties. We analyze the energy-magnetic field spectrum via an exact diagonalization method for a dilute gas of interacting magnons and detect up to 4- and 6-magnon bound states, hybridized with single magnons. This zoo of tunable interacting quasiparticles provides a unique platform to study decay and renormalization, reminiscent of the few-body problems found in cold-atom, nuclear, and particle physics.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1103/PhysRevLett.127.267201 | DOI Listing |
BMC Nephrol
December 2024
Head Doctor of the Dialysis Medical Center LLC, "Nephrocenter", Dovzhenka 3, Kyiv, 03057, Ukraine.
Background: The impact of protein-bound uremic toxins, specifically indoxyl sulfate (IS) on peritoneal dialysis (PD) complications remains controversial. This study aimed to explore the link between serum total IS (tIS) levels, proinflammatory cytokines in serum and peritoneal dialysis effluent (PDE), and PD technique survival.
Methods: In this prospective cohort study, 84 patients were followed up for three years and analyzed.
Bioorg Med Chem
December 2024
Department of Radiology, Washington University School of Medicine, St. Louis, MO 63110, United States. Electronic address:
The purinergic P2X ligand-gated ion channel 7 receptor (P2X7R) plays a critical role in various inflammatory processes and other diseases. Fast determination of compounds P2X7R binding potency and discovery of a promise PET radiotracer for imaging P2X7R require a P2X7R suitable radioligand for radioactive competitive binding assay. Herein, we designed and synthesized thirteen new P2X7R ligands and determined the in vitro binding potency.
View Article and Find Full Text PDFJ Environ Manage
December 2024
Department of Ecology, Engineering Research Center for Tropical and Subtropical Aquatic Ecological Engineering, Ministry of Education, Jinan University, Guangzhou, 510632, PR China. Electronic address:
Pyrite is considered as an effective and environmentally friendly substrate in constructed wetlands (CW) for wastewater treatment, but its application in recirculation stacking hybrid constructed wetlands (RSHCW) has been scarcely studied. This study uses varying amounts of pyrite as the substrate in RSHCW, leveraging the recirculation of wastewater to alter microenvironments such as dissolved oxygen (DO) and pH, to explore the potential mechanisms of nitrogen (N) and phosphorus (P) removal in pyrite-based RSHCW. The results show that as the proportion of pyrite increases, the removal rate of total phosphorus (TP) in the effluent also increases (25%→58%), significantly enhancing the deposition of iron-bound phosphorus (Fe-P) on the substrate, thereby turning CW into a P reservoir.
View Article and Find Full Text PDFCurr Opin Struct Biol
December 2024
Univ. Grenoble Alpes, CEA, CNRS, IBS, Grenoble, France. Electronic address:
Advances in the characterization of intrinsically disordered proteins (IDPs) have unveiled a remarkably complex and diverse interaction landscape, including coupled folding and binding, highly dynamic complexes, multivalent interactions, and even interactions between entirely disordered proteins. Here we review recent examples of IDP binding mechanisms elucidated by experimental techniques such as nuclear magnetic resonance spectroscopy, single-molecule Förster resonance energy transfer, and stopped-flow fluorescence. These techniques provide insights into the structural details of transition pathways and complex intermediates, and they capture the dynamics of IDPs within complexes.
View Article and Find Full Text PDFJ Leukoc Biol
December 2024
School of Life Sciences, Arizona State University, Phoenix, AZ.
Regulatory T cells can suppress activated T cell proliferation by direct cell-contact, although the exact mechanism is poorly understood. Identification of a Treg-specific cell surface molecule that mediates suppression would offer a unique target for cancer immunotherapy to inhibit Treg immunosuppressive function or deplete Tregs in the tumor microenvironment. In this study, we explored a method of whole cell immunization using a Treg-like cell line (MoT cells) to generate and screen monoclonal antibodies that bound cell surface proteins in their native conformations and functionally reversed Treg-mediated suppression.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!