AI Article Synopsis

  • The Bacillus Calmette-Guérin (BCG) vaccine, while effective for bladder cancer, has been linked to rare cases of mycotic arterial aneurysms.
  • A case study is presented involving a patient who experienced a ruptured abdominal aorta without an aneurysm after receiving BCG therapy years prior.
  • The patient was successfully treated with emergency aortic repair followed by a long course of antimycobacterial treatment due to confirmed infection, highlighting the need for vigilance among vascular surgeons regarding unusual aortic ruptures in patients previously treated with BCG.

Article Abstract

Bacillus Calmette-Guérin (BCG) vaccine has been successfully used to treat bladder cancer. However, sporadic cases of mycotic arterial aneurysms have been reported. These patients typically develop a infection of an existing aneurysm or graft. In the present report, we have described the case of a patient with a ruptured nonaneurysmal abdominal aorta years after intravesicular BCG therapy. Emergent aortic endograft repair was successful. After subsequent evaluation confirmed infection, the patient was treated with a prolonged course of antimycobacterial therapy. Vascular surgeons should maintain suspicion for atypical aortic ruptures in patients with exposure to intravesicular BCG therapy.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8731694PMC
http://dx.doi.org/10.1016/j.jvscit.2021.11.002DOI Listing

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