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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8648429PMC
http://dx.doi.org/10.5826/dpc.1104a122DOI Listing

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Article Synopsis
  • Neonatal alveolar lymphangioma (NAL) is a rare benign growth typically found in the mouths of newborns, especially those of African descent.
  • A case study discusses bilateral NAL with imaging follow-ups at 6 and 17 months, highlighting differential diagnoses like dental lamina cyst and hemangioma.
  • Accurate clinical identification of NAL is crucial, as biopsies are generally not needed, with follow-up recommended for one year or until the condition resolves.
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We report a newborn with neurocristic cutaneous hamartoma of the scalp. He was delivered at term via caesarean section due to a previous scar and presented at the neonatal unit on the fifth day with giant congenital nevi on the scalp and disseminated melanocytic nevi throughout the body. The MRI scan of the brain showed a defect at the occipital region with herniation of the occipital lobes and ventricles through the defect, with infratentorial brain parenchyma exhibiting normal signal return and intact cerebellum.

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Congenital Melanotic Macule of the Tongue: Report of Two Cases and Literature Review.

Head Neck Pathol

June 2023

Department of Oral Diagnosis and Pathology, School of Dentistry, Universidade Federal do Rio de Janeiro, R. Rodolpho Paulo Rocco, n. 325, 1st floor, Rio de Janeiro, RJ, Brazil.

Background: Congenital melanotic macule of the tongue (CMMT) has been described as a distinct entity, despite its unknown etiology. However, the diagnosis and management of affected newborns may challenge clinicians and pediatric dentists.

Methods: We document here the clinicopathological findings of two additional cases of CMMT.

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Article Synopsis
  • The case report presents a unique instance of melanotic neuroectodermal tumor of infancy (MNTI) in a 9-month-old girl, who also has tetralogy of Fallot (TOF) and congenital hypothyroidism (CH).
  • It was found that a lower dosage of levothyroxine (L-T4) for CH slowed MNTI growth, while the standardized dosage improved thyroid function but led to rapid MNTI progression.
  • The study highlights the significant impact of thyroid hormone on MNTI growth and emphasizes the need for careful management of co-existing health issues in pediatric MNTI cases.
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