Trigeminal neuropathy (TNO) manifests with unilateral or bilateral facio-oral sensory disturbances accompanied by pain and trigeminal nerve dysfunction. Although TNO may be posttraumatic or idiopathic, a thorough history and examination including magnetic resonance imaging is needed to exclude the multitude of secondary TNO causes. TNO-related pain necessitates multimodal treatment which in severe cases may encompass neurosurgical neuromodulation.
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Curr Opin Neurol
January 2025
Department of Neurology, Sri Ramachandra Institute of Higher Education and Research, Porur, Chennai, India.
Purpose Of Review: This review explores the phenomenology, pathogenesis, and nosology of headaches associated with infections, an often-overlooked yet clinically significant symptom. With the increasing recognition of secondary headaches in infections, understanding their clinical patterns, mechanisms, and classifications is crucial for accurate diagnosis and management.
Recent Findings: Headaches in infections are ubiquitous but vary in presentation, severity, and underlying mechanisms depending on the causative pathogen.
Front Immunol
January 2025
Key Laboratory of Freshwater Aquatic Genetic Resources, Ministry of Agriculture and Rural Affairs, Shanghai Ocean University, Shanghai, China.
Background: Shell and pearl formation in bivalves is a sophisticated biomineralization process that encompasses immunological and mineralization aspects, particularly during shell repair and the initial stages of pearl cultivation when a nucleus is inserted. Here, we describe a novel C-type lectin, HcLec1, isolated and characterized from the freshwater pearl mussel Lea.
Methods: Immune challenge, RNA interference (RNAi) experiments, ELISA, and antibacterial assays were employed to investigate the role of HcLec1 in innate immunity.
J Neurosci Methods
January 2025
College of Electronics and Information Engineering, Shenzhen University, Shenzhen, China; the Guangdong Key Laboratory of Intelligent Information Processing, Shenzhen, China. Electronic address:
Background: Autism spectrum disorder (ASD) is a neurodevelopmental disorder characterized by repetitive stereotypical behavior and social impairment. Early diagnosis is essential for developing a treatment plan for autism. Although multi-site data can expand the dataset to facilitate the process of data analysis, data heterogeneity between sites and the large amount of data make data analysis difficult.
View Article and Find Full Text PDFPLoS One
January 2025
SSL Lab, Dept. of CSE, Islamic University of Technology, Dhaka, Bangladesh.
Sharing cooking recipes is a great way to exchange culinary ideas and provide instructions for food preparation. However, categorizing raw recipes found online into appropriate food genres can be challenging due to a lack of adequate labeled data. In this study, we present a dataset named the "Assorted, Archetypal, and Annotated Two Million Extended (3A2M+) Cooking Recipe Dataset" that contains two million culinary recipes labeled in respective categories with extended named entities extracted from recipe descriptions.
View Article and Find Full Text PDFACS Nano
January 2025
School of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Natural skin receptors use ions as signal carriers, while most of the developed artificial tactile sensors utilize electrons as information carriers. To imitate the biological ionic sensing behavior, here, we present a kind of biomimetic, ionic, and fully passive mechanotransduction mechanism leveraging mechanical modulation of interfacial ionic p-n junction (IPNJ) through microchannels. Sensors based on this mechanism do not rely on an external power supply and can encode external tactile stimuli into highly analogous signal outputs to those of natural skin receptors, in terms of both signal type (i.
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