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Five new compounds from Zingiberis Rhizoma Recens and their anti-apoptotic activity. | LitMetric

AI Article Synopsis

  • Five new compounds were isolated from the acetone extract of Zingiberis Rhizoma Recens and named gingerol A, gingerol B, diphenylheptane glycoside A, and diphenylheptane glycoside B.
  • Their structures were determined using various spectroscopic methods including UV, IR, 1D NMR, 2D NMR, and HR-ESI-MS.
  • The new compounds showed potential health benefits by significantly reducing apoptosis and increasing survival rates in human normal lung epithelial cells when tested at a concentration of 10 μM.

Article Abstract

Five new compounds, named gingerol A ( and ), gingerol B (), diphenylheptane glycoside A () and diphenylheptane glycoside B (), were isolated from the acetone extract of Zingiberis Rhizoma Recens. The structures of new compounds were elucidated on the basis of spectroscopic methods including UV, IR, 1D NMR, 2D NMR and HR-ESI-MS. Compounds - could significantly decrease the apoptosis rate and increase the survival rate of human normal lung epithelial cells (BEAS-2B) at the concentration of 10 μM.

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Source
http://dx.doi.org/10.1080/10286020.2022.2026335DOI Listing

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