AI Article Synopsis

  • The study aimed to analyze the disease patterns, progression, and imaging traits in patients suffering from bilateral central serous chorioretinopathy (CSCR).
  • Out of 103 patients examined, 36 had bilateral CSCR at the start, with most showing symmetric disease, primarily complex rather than simple cases.
  • By the end of the follow-up, which averaged about 17.5 months, there were no significant differences in eye health metrics between the two eyes or any transitions from simple to complex CSCR.

Article Abstract

Purpose: To report the disease pattern, progression and imaging characteristics in eyes with bilateral central serous chorioretinopathy (CSCR).

Methods: This was a retrospective case review of bilateral CSCR patients with active disease in at least one eye. Multimodal imaging including fundus photography, fundus autofluorescence, optical coherence tomography (OCT), fluorescein and indocyanine angiography (FA/ICGA) was done at baseline and follow-up visits. Disease classification was done using recently described classification criteria. The degree of asymmetry in the disease distribution pattern at baseline and disease progression during follow-up visit with a minimum duration of 12 months was studied.

Results: Among 103 CSCR patients, 36 patients (34.95%) with mean age of 53.6 ± 10.5 years had bilateral CSCR at baseline. Five patients (13.9%) had asymmetrical disease i.e. simple in one eye and complex in fellow eye. The remaining 31 patients had symmetric disease (simple, 2; complex 29). Mean duration of follow up was 17.58 ± 13.84 months. There was no significant difference between both eye parameters at last follow up (best corrected visual acuity, BCVA; central macular thickness, CMT; and subfoveal choroidal thickness, SFCT) (all p > 0.05). At last follow up, 22 eyes (2 simple and 20 complex) remained active whereas none of the eyes converted from simple to complex CSCR.

Conclusion: Bilateral disease was more commonly seen with complex CSCR in contrast to simple CSCR. Moreover, disease distribution in complex CSCR had symmetric pattern if bilateral disease was present. None of the simple CSCR eyes converted to complex type.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9829729PMC
http://dx.doi.org/10.1038/s41433-021-01885-4DOI Listing

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