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Effect of hemodialysis on short-term outcomes after colon cancer surgery. | LitMetric

AI Article Synopsis

  • * Out of 1,372 patients studied, 19 (1.4%) were on hemodialysis, all of whom had poor health status and many had additional health issues; 78.9% underwent minimally invasive surgery.
  • * Results showed that hemodialysis patients experienced a significantly higher rate of postoperative complications (36.8%) compared to non-hemodialysis patients (15.5%), mainly due to infections, indicating the need for cautious perioperative management.

Article Abstract

Background: Hemodialysis patients who undergo surgery have a high risk of postoperative complications. The aim of this study was to determine whether colon cancer surgery can be safely performed in hemodialysis patients.

Methods: This multicenter retrospective study included 1372 patients who underwent elective curative resection surgery for colon cancer between April 2016 and March 2020.

Results: Of the total patients, 19 (1.4%) underwent hemodialysis, of whom 19 (100%) had poor performance status and 18 had comorbidities (94.7%). Minimally invasive surgery was performed in 78.9% of hemodialysis patients. The postoperative complication rate was significantly higher in hemodialysis than non-hemodialysis patients (36.8% vs. 15.5%, p = 0.009). All postoperative complications in the hemodialysis patients were infectious type. Multivariate analysis revealed a significant association of hemodialysis with complications (odds ratio, 2.9362; 95%CI, 1.1384-7.5730; p = 0.026).

Conclusion: Despite recent advances in perioperative management and minimally invasive surgery, it is necessary to be aware that short-term complications can still occur, especially infectious complications in hemodialysis patients.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8754322PMC
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0262531PLOS

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