Modified cellulose films are recommended to be used as carriers in preparing enzymatic membranes for penicillin-selective electrodes. The results of laboratory testing of the enzymatic penicillin-selective electrode based on the cellulose membrane with immobilized penicillinase are presented. In principle it was shown possible to use the enzymatic electrode in determining penicillin concentration in solutions. Dependence of the electrode reading on the buffer capacity was revealed. Optimal characteristics of the enzymatic membranes and the life-expectancy of the enzymatic electrode were determined.
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Sensors (Basel)
December 2024
Department of Mechanical Engineering, University of Michigan, 2350 Hayward St., Ann Arbor, MI 48109, USA.
In this study, a method for determining the optimal location and orientation of an implantable piezoelectric accelerometer on the short process of the incus is presented. The accelerometer is intended to be used as a replacement for an external microphone to enable totally implantable auditory prostheses. The optimal orientation of the sensor and the best attachment point are determined based on two criteria-maximum pressure sensitivity sum and minimum loudness level sum.
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December 2024
Department of Electrical and Computer Engineering, Bucknell University, Lewisburg, PA 17837, USA.
Micropillar array electrodes offer several advantages, such as enhanced mass transport, lower detection limits, and the potential for miniaturization, making them instrumental in the design and fabrication of electrochemical biosensors. The performance of these biosensors is influenced by electrode geometry, including parameters like shape and height, which affect surface area and overall sensitivity. In this study, we designed a microfluidic electrochemical biosensor featuring micropillar array electrodes, modeled in COMSOL Multiphysics.
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December 2024
Université de Lyon, UCBL1 Laboratoire Inter Universitaire de Biologie de la Motricité, EA 7424, 69100 Villeurbanne Cedex, France.
This study investigated muscle activation, shocks, and vibrations of the upper extremities during tennis serves between junior and adult tennis players. Thirty-five well-trained tennis players (15 juniors and 20 adults) performed 10 maximal successful tennis serves. Two triaxial accelerometers recorded the shock and vibration on the racket and the hand on the dominant side.
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December 2024
Research Group for Implantable Microsystems, Faculty of Information Technology & Bionics, Pázmány Péter Catholic University, H-1083 Budapest, Hungary.
The aim of this work is to incorporate lanthanide-cored upconversion nanoparticles (UCNP) into the surface of microengineered biomedical implants to create a spatially controlled and optically releasable model drug delivery device in an integrated fashion. Our approach enables silicone-based microelectrocorticography (ECoG) implants holding platinum/iridium recording sites to serve as a stable host of UCNPs. Nanoparticles excitable in the near-infrared (lower energy) regime and emitting visible (higher energy) light are utilized in a study.
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December 2024
Institute of Molecular Biology and Genetics, National Academy of Sciences of Ukraine, 03680 Kyiv, Ukraine.
This work presents the development of an amperometric biosensor for detecting aspartate aminotransferase (AST) activity in biological fluids using a platinum disk electrode as the working transducer. Optimal concentrations of substrates (aspartate, α-ketoglutarate) and the coenzyme (pyridoxal phosphate) were determined to ensure efficient biosensor operation. A semi-permeable poly-m-phenylenediamine membrane was applied to enhance selectivity against electroactive interferents.
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