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Effective Management Strategies for Primary Lymphedema of the Lower Extremities: Integrating Conservative and Surgical Therapies in Early and Late Stages.
Microsurgery
January 2025
Division of Plastic Surgery, China Medical University Hospital, Taichung, Taiwan.
Introduction: Lymphedema, a debilitating characterized by localized fluid retention and tissue swelling, results from abnormalities in the lymphatic system. In the case of primary lymphedema, this condition is attributed to malformations in lymphatic vessels or nodes, and it is marked by a relentless progression leading to irreversible tissue fibrosis after repetitive inflammation. Many questions regarding its treatment, such as the choice of the type of intervention and the timing, still remain unanswered.
View Article and Find Full Text PDFSuccessful surgical management of Leriche syndrome in a 30-year-old female patient: A rare case report.
Int J Surg Case Rep
January 2025
Department of Vascular Surgery, Faculty of Medicine, Aleppo University Hospital, University of Aleppo, Aleppo, Syria.
Introduction And Importance: Leriche syndrome (LS), or aortoiliac occlusive disease, is a rare form of peripheral arterial disease leading to claudication, impotence, and diminished femoral pulses due to atheromatous obstruction of the infrarenal aorta and common iliac arteries. Early identification is crucial as untreated LS can result in severe complications. Treatment primarily involves surgical interventions, with endovascular options considered as alternatives.
View Article and Find Full Text PDFAdaptation of functional gait parameters to a newly provided stiffness-optimized ankle-foot orthosis.
Clin Biomech (Bristol)
December 2024
Amsterdam UMC location University of Amsterdam, Rehabilitation Medicine, Meibergdreef 9, Amsterdam, the Netherlands; Amsterdam Movement Sciences, Rehabilitation and Development, Amsterdam, the Netherlands. Electronic address:
Background: Clinical decisions regarding ankle-foot-orthosis stiffness in people with calf muscle weakness are based on immediate evaluations, not taking gait adaptation into account. This study examined adaptation of step length, walking speed and energy cost of walking in the 3-months post-provision and whether individuals with higher gait variability adapt more compared to individuals with lower gait variability.
Methods: We conducted a post-hoc analysis in eighteen stiffness-optimized ankle-foot-orthosis users with bilateral calf muscle weakness.
Trisomy 26 in a Holstein calf with disorders of sex development.
Anim Genet
February 2025
Vetsuisse Faculty, Institute of Genetics, University of Bern, Bern, Switzerland.
Hypospadias occurs sporadically in male livestock and is characterized by a non-fused urethra during fetal development. In this study, perineal hypospadias, a bifid scrotum, penile hypoplasia, and bilateral abdominal cryptorchidism were diagnosed in a neonatal Holstein male calf. Septicemia was also suspected due to hypothermia, blurred conjunctivae, and loss of sucking and swallowing reflexes.
View Article and Find Full Text PDFCase Report: Charcot-marie-tooth disease caused by a gene mutation - novel insights into pathogenicity and treatment.
Front Genet
October 2024
Department of Neurology, Taizhou Hospital of Zhejiang Province Affiliated to Wenzhou Medical University, Taizhou, China.
Charcot-Marie-Tooth disease (CMT) is a hereditary peripheral neuropathy involving approximately 80 pathogenic genes. Whole-exome sequencing (WES) and confirmatory Sanger sequencing analysis was applied to identify the disease-causing mutations in a Chinese patient with lower limb weakness. We present an 18-year-old male with a 2.
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