A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the potential drug interaction of cyclosporine with ciprofloxacin and the need to exercise caution while prescribing antibiotics with cyclosporine.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8706601 | PMC |
| http://dx.doi.org/10.4103/jpn.JPN_130_20 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Article Synopsis
- A 29-year-old Korean woman with chronic aplastic anemia experienced seizures linked to complications from cyclosporine treatment.
- The condition was identified as posterior reversible encephalopathy syndrome due to unpredictable accumulation of the drug.
- This case highlights the importance of closely monitoring cyclosporine levels and making careful dose adjustments to avoid complications.
Cyclosporine-Induced Posterior Reversible Encephalopathy Syndrome: An Adverse Effect in a Patient With Atopic Dermatitis.
Cutis
March 2023
Dr. C.P. Dunn is from the Division of Allergy and Infectious Diseases, Department of Medicine, University of Washington, Seattle. Dr. C.L. Dunn is from the Department of Dermatology, KCU-GME/ADCS Consortium, Maitland, Florida. Dr. Petroni is from the Northwest Allergy and Asthma Center, University of Washington, Seattle.
Case report: Cyclosporine A-induced extrapyramidal syndrome following hematopoietic stem cell transplantation.
Front Neurol
April 2023
Division of Neurology, Department of Pediatrics, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman.
Introduction: Cyclosporine A-associated neurotoxicity has been reported in up to 40% of patients and its wide range of neurological adverse effects have been reported, ranging from mild tremors to fatal leukoencephalopathy. Extrapyramidal (EP) neurotoxicity is a rare manifestation of cyclosporine. Cyclosporine-induced extrapyramidal syndrome remains a rare adverse reaction.
View Article and Find Full Text PDFCyclosporine-induced Leukoencephalopathy Precipitated Following Interaction with Ciprofloxacin.
J Pediatr Neurosci
July 2021
Department of Diagnostic and Interventional Radiology, Columbia Asia Hospitals, Bengaluru, Karnataka, India.
A bone marrow transplant recipient on cyclosporine initiated on ciprofloxacin for a renal abscess presented with encephalopathy, right hemiparesis, and multiorgan dysfunction. Imaging revealed white matter signal changes characteristic of cyclosporine leukoencephalopathy. This case illustrates the potential drug interaction of cyclosporine with ciprofloxacin and the need to exercise caution while prescribing antibiotics with cyclosporine.
View Article and Find Full Text PDFCyclosporine-induced toxic leukoencephalopathy in toxic epidermal necrolysis.
Int J Dermatol
February 2019
Department of Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!