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Leptin Levels in Gingival Crevicular Fluid during Orthodontic Tooth Movement. | LitMetric

Aim: To evaluate the levels of leptin in gingival crevicular fluid (GCF) during orthodontic tooth movement and to find the role of leptin as a mediator for tooth movement.

Materials And Methods: GCF was collected from 25 subjects and the levels of leptin in it were measured. Sample (A) pretreatment, (B) 6 h after applying retractive orthodontic force from right side canine, (C) without retractive force from left side canine, and after 21 days from right canine (D), and left canine (E).

Results: GCF Leptin concentration in pretreatment, 6 h control and 21 day control were all similar. GCF leptin concentration at 6 h test tooth site was increased which was statistically significant. GCF leptin concentration in 21 day test tooth was decreased only a little than the control tooth which shows statistically no difference.

Conclusion: Leptin is one of the mediators of orthodontic tooth movement.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8686992PMC
http://dx.doi.org/10.4103/jpbs.jpbs_285_21DOI Listing

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