Basing on routine laboratory diagnosis of serum antibodies to the human immunodeficiency virus (HIV-1) in the years 1985 and 1986, the monthly detection rate of infection amounts to 50 persons on an average in the region of Frankfurt/FRG. The relation of female to male persons changed from 1:7 to 1:3 during one year. This might be influenced by a screening programme performed with female prostitutes who are found seropositive in about 2.5%. In December 1986, the first case of an HIV-2 infection was recorded. The clinical examination of HIV-infected patients admitted to the City Hospital of Offenbach/FRG revealed striking signs in about 35-40%, of AIDS in 6%. The infected persons belong to risk groups. No positive result was seen in pregnant women (n = 1100), medical staff (n = 405) and patients requiring renal transplants (n = 115) who do not belong to the risk groups.
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