AI Article Synopsis
- A rare case of laryngotracheal granulomatous disease due to sporotrichosis is described in an immunocompromised patient.
- The patient, a 72-year-old woman with a history of handling roses, experienced hoarseness and voice changes for a year.
- After diagnosis through endoscopy and biopsy, she received long-term itraconazole treatment, resulting in improvement and a reduction in granulomas.
- The findings highlight the need for a thorough differential diagnosis in similar cases and the importance of specialized testing and prolonged antifungal treatment.
Article Abstract
Objective: To describe a rare presentation of laryngotracheal granulomatous disease secondary to sporotrichosis.
Methods: The authors report a case of laryngeal sporotrichosis in an immunocompromised patient, with accompanying endoscopic images and pathology.
Results/case: A 72-year-old immunocompromised female with a history of rose-handling presented with a year of hoarseness and breathy voice. Flexible nasolaryngoscopy showed diffuse nodularity; biopsy of the lesions demonstrated granulomatous inflammatory changes, and fungal culture grew . Long-term itraconazole treatment was initiated, with improvement in dysphonia and few residual granulomas on follow-up examination.
Conclusion: When evaluating granulomatous disease of the airway, a broad differential including infectious or inflammatory etiologies should be considered, especially in immunocompromised patients. Adequate tissue samples should be collected to facilitate special staining. The current recommendations for laryngeal sporotrichosis include treatment with a prolonged course of itraconazole.
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| http://dx.doi.org/10.1177/00034894211073002 | DOI Listing |
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