Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Coronavirus Cryptic Landscape and Draft Genome of a Novel CoV Clade Related to MERS From Bats Circulating in Northeastern Brazil.
J Med Virol
January 2025
Department of Morphology and Genetics, Federal University of São Paulo, São Paulo-SP, Brazil.
We identified seven distinct coronaviruses (CoVs) in bats from Brazil, classified into 229E-related (Alpha-CoV), Nobecovirus, Sarbecovirus, and Merbecovirus (Beta-CoV), including one closely related to MERS-like CoV with 82.8% genome coverage. To accomplish this, we screened 423 oral and rectal swabs from 16 different bat species using molecular assays, RNA sequencing, and evolutionary analysis.
View Article and Find Full Text PDFCombining genomics and epidemiology to investigate a zoonotic outbreak of rabies in Romblon Province, Philippines.
Nat Commun
December 2024
Boyd Orr Centre for Population and Ecosystem Health, School of Biodiversity, One Health & Veterinary Medicine, College of Medical, Veterinary & Life Sciences, University of Glasgow, Glasgow, UK.
Rabies is a viral zoonosis that kills thousands of people annually in low- and middle-income countries across Africa and Asia where domestic dogs are the reservoir. 'Zero by 30', the global strategy to end dog-mediated human rabies, promotes a One Health approach underpinned by mass dog vaccination, post-exposure vaccination of bite victims, robust surveillance and community engagement. Using Integrated Bite Case Management (IBCM) and whole genome sequencing (WGS), we enhanced rabies surveillance to detect an outbreak in a formerly rabies-free island province in the Philippines.
View Article and Find Full Text PDFDraft genomes of two contemporary strains of .
Microbiol Resour Announc
January 2025
Vector Borne Diseases, Virology Department, Animal Plant and Health Agency, Addlestone, Surrey, United Kingdom.
, major cause of bovine babesiosis with zoonotic potential, was analyzed through genomes Bdiv23B and Bdiv24B following Illumina sequencing of DNA extracted from PCR-positive cattle blood. The genomes comprised 3888 and 4032 predicted coding sequences, respectively, comparable to the reference genome, Rouen 1987, highlighting genomic consistency across isolates.
View Article and Find Full Text PDFAntiviral Potential and In Silico Insights of Polyphenols as Sustainable Phytopharmaceuticals: A Comprehensive Review.
Chem Biodivers
December 2024
School of Life Sciences, Swami Vivekananda University, Barrackpore, Kolkata, India.
Polyphenols, particularly flavonoids, are reported to have health-promoting, disease-preventing abilities and several polyphenols having a wide spectrum of antiviral activities can be explored for preventive and/or therapeutic purposes. We have compiled the updated literature of diverse polyphenols active against common viral diseases, including herpes, hepatitis, influenza, rota and SARS-corona-viruses. The antiviral activity of bioactive polyphenols depends on the hydroxyl and ester groups of polyphenol molecules, as compounds with five or more hydroxyl groups and three specific methoxy groups showed antiviral potential, like anti-rabies activity.
View Article and Find Full Text PDFIntegrating one health strategies for rabies control: Insights from Jackal-mediated human rabies in Northeast India.
Comp Immunol Microbiol Infect Dis
January 2025
Department of Neurovirology, National Institute of Mental Health and Neurosciences, Bangalore 560029, India. Electronic address:
Article Synopsis
- Rabies is a deadly disease caused by Lyssavirus, primarily transmitted to humans through domestic dogs, but wildlife like jackals also play a role, as shown in a case from India.
- RNA from a rabid jackal and a human victim was analyzed using real-time PCR and whole genome sequencing to understand the virus's characteristics.
- Results indicated that both the jackal and human carried rabies virus from the Arctic AL1a lineage, suggesting a connection to dog strains in the region, emphasizing the need for improved rabies control measures.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!