The effect of propofol on intraocular pressure (IOP) was measured in 25 patients presenting for elective non-ophthalmological surgery when propofol was used for the induction and maintenance of anaesthesia (together with 67% nitrous oxide in oxygen, and vecuronium). Normocapnia was maintained. After induction of anaesthesia, intraocular pressure was significantly lower than the baseline value; during maintenance IOP never exceeded the preinduction value. There was a temporary decrease in arterial pressure after induction. In nine patients a cutaneous flush was observed and in seven patients there was discomfort on injection. Spontaneous movement in 20% and hiccup in 12% of the patients were observed at the time of tracheal intubation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1093/bja/59.12.1514 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Evaluating vitamin C-related gene-environment and metabolite-environment interaction effects on intraocular pressure in the Canadian Longitudinal Study on Aging.
BMC Genom Data
January 2025
School of Epidemiology and Public Health, University of Ottawa, 600 Peter Morand Crescent, Office 101E, Ottawa, Ontario, K1G 5Z3, Canada.
High intraocular pressure (IOP) is an important risk factor for glaucoma, which is influenced by genetic and environmental factors. However, the etiology of high IOP remains uncertain. Metabolites are compounds involved in metabolism which provide a link between the internal (genetic) and external environments.
View Article and Find Full Text PDFTemporal impacts of diverse concentrations of pilocarpine ophthalmic solution on human accommodation.
Clin Exp Optom
January 2025
Eye Institute and Department of Ophthalmology, Eye & ENT Hospital, Fudan University, Shanghai, China.
Clinical Relevance: Accommodation is crucial for clear near vision and is predominantly affected by presbyopia. The ability to modulate accommodative function with eye drops could offer a pharmacological approach to manage presbyopia.
Background: To investigate the effects of different concentrations of pilocarpine eye drops on ocular accommodation in young volunteers.
Retinal and Choroidal Circulation Impairments in Fanconi Anemia.
Am J Ophthalmol
January 2025
Hacettepe University School of Medicine, Department of Ophthalmology, Ankara, Turkey.
Objective: To evaluate the effects of Fanconi anemia (FA) on retinal and choroidal microvasculature using Optical Coherence Tomography (OCT) and Optical Coherence Tomography Angiography (OCTA).
Design: Cohort study with age-matched controls.
Subjects And Participants: This study included 11 eyes from 11 patients diagnosed with FA and 12 eyes from 12 age-matched healthy controls.
On QSPR analysis of glaucoma drugs using machine learning with XGBoost and regression models.
Comput Biol Med
January 2025
Department of Mathematics and Statistics, The University of Lahore, Lahore Campus, Pakistan. Electronic address:
Glaucoma is an irreversible, progressive, degenerative eye disorder arising because of increased intraocular pressure, resulting in eventual vision loss if untreated. The QSPR relates, mathematically, by employing various algorithms, a specified property of a molecule that arises either from physical, chemical, or biological phenomena using various aspects of its structure. Here in, a similar application based on topological indices and inferences derived from the structure for the calculation of different drug properties like molar refractivity, refractive index, enthalpy, boiling points, molecular weight, and polarizability is presented.
View Article and Find Full Text PDFShort-term orthokeratology effects on corneal biomechanics with a focus on SPA1 and stress-strain index (SSI) parameters in pediatric myopia.
Arq Bras Oftalmol
January 2025
Department of Ophthalmology, Guangdong Eye Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences. No. 106 Zhongshan Er Road, Guangzhou 510080, China.
Purpose: Although the orthokeratology effects on corneal biomechanics have been proven with clinical trials, reports of stiffness parameter change are scarce. This study investigated the short-term orthokeratology effects in pediatric myopia and compared stiffness parameter changes to those published in recent clinical investigations. This prospective study aimed to investigate corneal biomechanics changes induced by short-term overnight orthokeratology treatment, focusing on stiffness parameter at A1 and stress-strain index.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!