AI Article Synopsis

  • * A study involving 200 ME/CFS patients assessed the effectiveness of oxygen-ozone autohemotherapy (O-O-AHT) on fatigue reduction, using a scoring questionnaire before and after a month of treatment.
  • * Results showed that female patients experienced significantly better improvements in fatigue compared to male patients, especially in the 14-29 age group, indicating a gender difference in treatment response.

Article Abstract

(1) Background: Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) is a syndrome that has fatigue as its major symptom. Evidence suggests that ozone is able to relieve ME/CFS-related fatigue in affected patients. (2) Objective: To evaluate whether differences exist between males and females in ozone therapy outputs in ME/CFS. (3) Methods: In total, 200 patients previously diagnosed with ME/CFS (mean age 33 ± 13 SD years) underwent treatment with oxygen-ozone autohemotherapy (O-O-AHT). Fatigue was investigated via an FSS 7-scoring questionnaire before and following 1 month after treatment. (4) Results: The Mann-Whitney test (MW test) assessed the significance of this difference (H = 13.8041, = 0.0002), and female patients showed better outcomes than males. This difference was particularly striking in the youngest age cohort (14-29 years), and a KW test resulted in H = 7.1609, = 0.007 for the Δ = 28.3% (males = 3.8, females = 5.3). (5) Conclusions: When treated with O-O-AHT, females respond better than males.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8745436PMC
http://dx.doi.org/10.3390/jcm11010173DOI Listing

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