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TUBE Project: Transport-Derived Ultrafines and the Brain Effects. | LitMetric

AI Article Synopsis

  • Air pollutants are known to adversely affect the respiratory and cardiovascular systems, but recent studies indicate they may also harm the brain, being linked to neurological diseases like Alzheimer's.
  • The key contributors to these effects seem to be ultrafine particles (UFPs), yet there’s limited regulation and knowledge about their smallest fractions and the semivolatile components of emissions.
  • The TUBE project aims to investigate these harmful ultrafine pollutants and their impacts on brain health, providing crucial information to inform better emission legislation and public health decisions.

Article Abstract

The adverse effects of air pollutants on the respiratory and cardiovascular systems are unquestionable. However, in recent years, indications of effects beyond these organ systems have become more evident. Traffic-related air pollution has been linked with neurological diseases, exacerbated cognitive dysfunction, and Alzheimer's disease. However, the exact air pollutant compositions and exposure scenarios leading to these adverse health effects are not known. Although several components of air pollution may be at play, recent experimental studies point to a key role of ultrafine particles (UFPs). While the importance of UFPs has been recognized, almost nothing is known about the smallest fraction of UFPs, and only >23 nm emissions are regulated in the EU. Moreover, the role of the semivolatile fraction of the emissions has been neglected. The Transport-Derived Ultrafines and the Brain Effects (TUBE) project will increase knowledge on harmful ultrafine air pollutants, as well as semivolatile compounds related to adverse health effects. By including all the major current combustion and emission control technologies, the TUBE project aims to provide new information on the adverse health effects of current traffic, as well as information for decision makers to develop more effective emission legislation. Most importantly, the TUBE project will include adverse health effects beyond the respiratory system; TUBE will assess how air pollution affects the brain and how air pollution particles might be removed from the brain. The purpose of this report is to describe the TUBE project, its background, and its goals.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8751045PMC
http://dx.doi.org/10.3390/ijerph19010311DOI Listing

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