Nanoplasmonic Strip Test for Salivary Glucose Monitoring.

Nanomaterials (Basel)

Nanobiointeractions & Nanodiagnostics, Istituto Italiano di Tecnologia (IIT), via Morego, 30-16163 Genova, Italy.

Published: December 2021

Nowadays, there is an increasing interest in Point-of-care (POC) devices for the noninvasive glucose assessment. Despite the recent progress in glucose self-monitoring, commercially available devices still use invasive samples such as blood or interstitial fluids, and they are not equipment-free and affordable for the whole population. Here, we report a fully integrated strip test for the semi-quantitative detection of glucose in whole saliva. The colorimetric mechanism consists of an enzyme-mediated reshaping of multibranched gold nanoparticles (MGNPs) into nanospheres with an associated plasmonic shift and consequent blue-to-red color change, clearly detectable in less than 10 min.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8746375PMC
http://dx.doi.org/10.3390/nano12010105DOI Listing

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