Previous experimental work showed that young adults reporting loneliness performed less well on emotion recognition tasks (Diagnostic Analysis of Nonverbal Accuracy [DANVA-2]) if they were framed as indicators of social aptitude, but not when the same tasks were framed as indexing academic aptitude. Such findings suggested that undergraduates reporting loneliness possessed the social monitoring skills necessary to read the emotions underlying others' facial expressions, but that they choked under social pressure. It has also been found that undergraduates reporting loneliness have better recall for both positive and negative social information than their non-lonely counterparts. Whether those effects are evident across different age groups has not been examined. Using data from the British Broadcasting Corporation (BBC) Loneliness Experiment that included participants aged 16-99 years ( = 54,060), we (i) test for replication in a larger worldwide sample and (ii) extend those linear model analyses to other age groups. We found only effects for participants aged 25-34 years: In this age group, loneliness was associated with increased recall of negative individual information, and with choking under social pressure during the emotion recognition task; those effects were small. We did not find any such effects among participants in other age groups. Our findings suggest that different cognitive processes may be associated with loneliness in different age groups, highlighting the importance of life-course approaches in this area.
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http://dx.doi.org/10.1177/0165025420979369 | DOI Listing |
Eur J Obstet Gynecol Reprod Biol
January 2025
Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Southern California, Los Angeles, CA, USA; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Los Angeles General Medical Center, Los Angeles, CA, USA; Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA. Electronic address:
Objective: To assess clinical and obstetric characteristics associated with pregnant patients with a diagnosis of attention-deficit hyperactivity disorder (ADHD).
Methods: This serial cross-sectional study queried the Agency of Healthcare Research and Quality's Healthcare Cost and Utilization Project National Inpatient Sample. The study population was 16,759,786 hospital deliveries from 2016 to 2020.
Psychoneuroendocrinology
January 2025
Department of Experimental Clinical and Health Psychology, Ghent University, Ghent, Belgium. Electronic address:
Telomere length (TL) is considered a biomarker of aging, and short TL in leukocytes is related to age and stress-related health problems. Cumulative lifetime stress exposure has also been associated with shorter TL and age-related health problems, but the mechanisms are not well understood. We tested in 108 individuals whether shorter TL in leukocytes is observed in individuals with the GABRA6 TT genotype, which has been associated with dysregulation of hypothalamic-pituitary-adrenal axis activity (the main biological stress system) compared to the CC genotype.
View Article and Find Full Text PDFKnee
January 2025
IULS-University Institute for Locomotion and Sports, Pasteur 2 Hospital, University Côte d'Azur, Nice, France; ICARE Team, Côte d'Azur University, Inserm, CNRS, Valrose Institute of Biology, Nice, France. Electronic address:
Background: Several studies have demonstrated the interest in patient-specific custom cutting guides in total knee arthroplasty (TKA), but clinical improvement remains debated. The purpose of this study was to evaluate the functional outcomes (Forgotten Joint Score, FJS) of patients undergoing individualized TKA compared with those receiving off-the-shelf (OTS) implants, both using patient-specific cutting guides with personalized alignment over a minimum follow up period of 12 months. We hypothesized that individualized TKA demonstrates significantly better functional outcomes than OTS TKA (FJS and percentage of patients reaching the minimum clinically important difference).
View Article and Find Full Text PDFExpert Opin Investig Drugs
January 2025
School of Pharmacy and Medical Sciences, Griffith University, Brisbane, Australia.
Introduction: Parkinson's disease (PD) is a common neurodegenerative disease. Glucagon-Like-Peptide-1 (GLP-1) receptor agonists decrease the incidence of developing PD, and are being considered for the treatment of PD.
Areas Covered: A phase 2 clinical trial of lixisenatide, a GLP-1 receptor agonist, in the early stages of PD.
JMIR Cardio
January 2025
Medicine Faculty, University of Geneva, Geneva, Switzerland.
Background: Medication nonadherence remains a significant challenge in the management of chronic conditions, often leading to suboptimal treatment outcomes and increased health care costs. Innovative interventions that address the underlying factors contributing to nonadherence are needed. Gamified mobile apps have shown promise in promoting behavior change and engagement.
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