Total Synthesis of Oxepin and Dihydrooxepin Containing Natural Products.

Synthesis (Stuttg)

Institute of Organic Chemistry and Center for Molecular Biosciences, Leopold-Franzens-University Innsbruck, Innrain 80-82, 6020 Innsbruck, Austria.

Published: June 2021

The construction of oxepin and dihydrooxepin containing natural products represents a challenging task in total synthesis. In the last decades, a variety of synthetic methods have been reported for the installation of these structural motifs. Herein, we provide an overview of synthetic methods and strategies to construct these motifs in the context of natural product synthesis and highlight the key steps of each example.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7612190PMC
http://dx.doi.org/10.1055/s-0037-1610776DOI Listing

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