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Switching to an Intravitreal Dexamethasone Implant after Intravitreal Anti-VEGF Therapy for Diabetic Macular Edema: A Review.
Life (Basel)
June 2024
Eye Clinic, Department of Surgical Sciences, University of Cagliari, 09124 Cagliari, CA, Italy.
Among working-age people, diabetic retinopathy and diabetic macular edema are currently considered the main causes of blindness. Nowadays, intravitreal injections are widely acknowledged as a significant milestone in ophthalmology, especially for the treatment of several retinal diseases, including diabetic macular edema. In particular, anti-vascular endothelial growth factor (VEGF) agents are typically the first line of treatment; however, monthly injections are required, at least, during the loading dosage.
View Article and Find Full Text PDFUsing dexamethasone wisely in invasively ventilated preterm infants.
Pediatr Pulmonol
April 2022
Department of Pediatrics, The University of Alabama at Birmingham, Birmingham, Alabama, USA.
Update on the "Choosing Wisely" initiative in infectious diseases in Germany.
Infection
June 2020
Division of Infectious Diseases, Department of Internal Medicine, University of Cologne, Cologne, Germany.
Purpose: The Choosing Wisely initiative is an international campaign addressing over- and underuse of diagnostic and therapeutic measures in infectious diseases among others. Since 2016, the German Society for Infectious Diseases (DGI) has constantly designed new items in this regard. Here we report the most recent recommendations.
View Article and Find Full Text PDFPrompt Improvement of an Enlarging Pigment Epithelial Detachment Following Intravitreal Dexamethasone in Neovascular Age-Related Macular Degeneration.
J Vitreoretin Dis
December 2019
Department of Ophthalmology, Duke University Medical Center, Durham, NC, USA.
Purpose: This report discusses a case of neovascular age-related macular degeneration with mixed serous pigment epithelial detachment (PED) that was unresponsive to antivascular endothelial growth injections but responded to the addition of intravitreal steroid injection.
Methods: We report a case.
Results: A 75-year-old woman with neovascular age-related macular degeneration developed a mixed serous PED in her right eye.
Inter-hospital variation in the utilization of diagnostics and their proportionality in the management of adult community-acquired pneumonia.
Pneumonia (Nathan)
December 2018
7Division of Pharmacoepidemiology and Clinical Pharmacology, University of Utrecht, Utrecht, The Netherlands.
Background: Utilization of diagnostics and biomarkers are the second largest cost drivers in the management of patients hospitalized with community-acquired pneumonia (CAP). The present study aimed to systematically assess the inter-hospital variation in these cost drivers in relation to antibiotic use in CAP.
Methods: Detailed resource utilization data from 300 patients who participated in a multicenter placebo-controlled trial investigating dexamethasone as adjunctive treatment for community-acquired pneumonia was grouped into 3 categories: clinical chemistry testing, radiological exams, and microbiological testing.
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