Purpose: To determine through a feasibility study whether anterior and posterior corneal arc length and cross-sectional area measured using anterior segment ocular coherence tomography (AS-OCT) can distinguish between healthy and keratoconic corneas.
Methods: Patients diagnosed with keratoconus along with healthy controls underwent AS-OCT. ImageJ was used to determine the central 6 mm anterior and posterior corneal arc lengths and cross-sectional areas. Each length and area was then divided into 1-mm segment and relative differences compared.
Results: Twenty-five eyes from 15 patients with keratoconus, along with 25 eyes from 14 healthy controls were enrolled. There was a statistically significant difference in anterior and posterior corneal arc lengths as well as corneal cross-sectional area (p = 0.006, p = 0.005, p = 0.01, respectively). When selecting for the less advanced keratoconus eye, it was noted that posterior corneal arc length was longer in the paracentral temporal segment (1003 vs. 1010 µm, p = 0.04) and that greater change in corneal cross-sectional areas occurred between adjacent segments in less advanced keratoconus eyes.
Conclusion: AS-OCT is capable of reliably measuring corneal arc lengths in patients with keratoconus and healthy patients. Both anterior and posterior corneal arc lengths along with central cross-sectional areas are statistically different between healthy and keratoconus eyes.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s10792-021-02210-4 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Double intrastromal corneal ring segment implantation: a new approach for improved clinical outcomes in keratoconus patients.
Int J Ophthalmol
November 2024
Center of Excellence in Ophthalmology, Pará de Minas 35660-017, Brazil.
Aim: To evaluate the clinical outcomes after subsequent implantation of a new intrastromal corneal ring segment (ICRS) model followed by an additional short-arc ICRS implant in keratoconus patients.
Methods: This retrospective single-arm cohort study evaluated 25 eyes of 21 keratoconus patients implanted with the new ICRS followed by 140-arch length ICRS (140-ICRS) implantation. Uncorrected distance visual acuity (UDVA, logMAR), corrected distance visual acuity (CDVA, logMAR), sphere, astigmatism, keratometry, spherical equivalent (SE), and asphericity were compared preoperatively and postoperatively after both ICRS implantation.
Effectiveness and biocompatibility of a novel Schlemm's canal microstent for glaucoma management.
Sci Rep
October 2024
Zhengzhou University People's Hospital, Henan Provincial People's Hospital, Henan Eye Hospital, Henan Eye Institute, No. 7 Weiwu Road, Zhengzhou, 450003, Henan, China.
To evaluate the effectiveness and biocompatibility of Wistend, a novel Schlemm's canal (SC) microstent made of Nitinol designed to improve aqueous humor outflow. New Zealand white (NZW) rabbits were divided into blank, sham-operated and Wistend groups. ICare Tonovet Plus, swept-source optical coherence tomography (SS-OCT), slit lamp biomicroscopy, retinal camera and scanning electron microscopy (SEM) were used for preoperative and postoperative observations.
View Article and Find Full Text PDFOcular genetics in the Japanese population.
Jpn J Ophthalmol
September 2024
Hamamatsu University School of Medicine, 1-20-1 Handayama, Chuo-ku, Hamamatsu city, Shizuoka, 431-3192, Japan.
Article Synopsis
- * Recent advancements in ocular genetics include identifying specific mutations, such as those in the EYS gene, which is often responsible for retinitis pigmentosa (RP), and exploring complex gene structures associated with other eye conditions.
- * Effective genome medicine relies on accurate patient diagnosis, understanding genetic patterns, and providing thorough genetic counseling, emphasizing the importance of clear communication between healthcare providers and patients regarding genetic diseases.
[Influence of screen brightness on reading in dry eye patients].
J Fr Ophtalmol
November 2024
IHU FOReSIGHT, Inserm-DHOS CIC 1423, Quinze-Vingts National Ophthalmology Hospital, Paris, France; Inserm, U968, UMR_S968, Institut de la Vision, CNRS, UMR 7210, CHNO des Quinze-Vingts, Inserm-DHOS CIC 503, UPMC University of Paris 06, Paris, France; Department of Ophthalmology, Ambroise-Paré Hospital, AP-HP, University of Versailles Saint-Quentin-en-Yvelines, Versailles, France.
Purpose: This study examines the impact of dry eye on screen reading, with an emphasis on glare and visual comfort for patients.
Population And Methods: We recruited ten patients with dry eye and nine healthy controls. Clinical signs of dry eye were quantified to determine the quality of the tear film and corneal aberrations.
Could Automated Objective Measurements Acquired at the Preoperative Stage Estimate the Corrected Distance Visual Acuity after Corneal Cross-Linking in Keratoconus?
Ophthalmol Ther
October 2024
Department of Cataract and Refractive Surgery, University Eye Hospital Svjetlost, 10000, Zagreb, Croatia.
Introduction: Objective markers describing corneal optical density (COD), thinnest corneal thickness (TCT), and anterior (ARC) and posterior (PRC) surface radii over the 3 mm thinnest region of the cornea were investigated to provide a model for estimating corrected distance visual acuity (CDVA) after corneal cross-linking (CXL) in keratoconus.
Methods: CDVA, COD, TCT, ARC, and PRC were monitored (using Pentacam™) over 1 year in patients with (1) keratoconus treated with routine CXL (2) relatively stable untreated keratoconus, and (3) age/gender-matched controls.
Results: In group 1 (n = 77), the median logMAR CDVA (mode, interquartile range) improved significantly (p < 0.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!