AI Article Synopsis
- Symptomatic BK polyomavirus (BKPyV) infections are frequently seen in patients with weakened immune systems, particularly those who have undergone hematopoietic cell transplants.
- The study reveals complete BKPyV genomes collected from these immunocompromised patients in the U.S., showing that they had non-subtype I strains of the virus.
- Analytical methods used included amplification, next-generation sequencing, and phylogenetic analysis to characterize the viral strains.
Article Abstract
Symptomatic BK polyomavirus (BKPyV) infections are common and relevant in immunocompromised patients. Here, we present full-length BKPyV genomes from samples from patients who received hematopoietic cell transplants in the United States. These individuals had non-subtype I BKPyV, as determined by amplification, next-generation sequencing, and phylogenetic analysis.
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Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8759406 | PMC |
| http://dx.doi.org/10.1128/mra.01053-21 | DOI Listing |
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