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| http://dx.doi.org/10.1002/emp2.12610 | DOI Listing |
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Trends and ethnic disparity in endometrial cancer mortality in South Africa (1999-2018): A population-based Age-period-cohort and Join point regression analyses.
PLoS One
January 2025
Division of Epidemiology and Biostatistics, School of Public Health, University of Witwatersrand, Johannesburg, South Africa.
Background: Endometrial cancer is the sixth leading cause of cancer among females and about 97,000 global deaths of endometrial cancer. The changes in the trends of obesity, fertility rates and other risk factors in South Africa (SA) may impact the endometrial cancer trends. The aim of this study was to utilise the age period cohort and join point regression modelling to evaluate the national and ethnic trends in endometrial cancer mortality in South Africa over a 20year period (1999-2018).
View Article and Find Full Text PDFAGDMP1 alleviates insulin resistance by modulating heat shock protein 60-mediated IRS-1/AKT/GLUT4 pathway and adipose inflammation: A potential therapeutic peptide for gestational diabetes mellitus.
FASEB J
January 2025
Changzhou Maternal and Child Health Care Hospital, Changzhou Medical Center, Nanjing Medical University, Changzhou, Jiangsu, China.
Gestational Diabetes Mellitus (GDM) is the most frequent complication during pregnancy. Pharmacological interventions, such as peptide drugs that focused on improving the insulin sensitivity might be promising in the prevention and treatment of GDM. In this study, we aimed to investigate the role and mechanism of a novel peptide, named AGDMP1 (Anti-GDM peptide 1), which we previously identified lower in the serum of GDM patients using mass spectrometry, on the adipose insulin resistance in GDM.
View Article and Find Full Text PDFNeonatal Nutrition and Brain Structure at 7 Years in Children Born Very Preterm.
JAMA Netw Open
January 2025
Liggins Institute, University of Auckland, Auckland, New Zealand.
Importance: Neonatal protein intake following very preterm birth has long lasting effects on brain development. However, it is uncertain whether these effects are associated with improved or impaired brain maturation.
Objective: To assess the association of neonatal protein intake following very preterm birth with brain structure at 7 years of age.
Incidence Rate Trends of Breast Cancer Overall and by Molecular Subtype by Race and Ethnicity and Age.
JAMA Netw Open
January 2025
Division of Public Health Sciences, Fred Hutchinson Cancer Center, Seattle, Washington.
Importance: Black and Hispanic women in the US experience higher incidence rates of aggressive molecular subtypes of breast cancer, including triple-negative disease. However, how these rates are changing, particularly across different age groups, has not been well documented.
Objective: To assess changes in overall and subtype-specific breast cancer incidence rates in the US by age and race and ethnicity.
Gender Differences in Barriers in Career Development Among a Cohort of Dental Researchers. A Cross-Sectional Study.
J Dent Educ
January 2025
School of Dental Medicine, University at Buffalo, Buffalo, New York, USA.
Background: This cross-sectional study investigated gender differences in barriers to career development among dental researchers and between academic and non-academic women.
Methods: An anonymous 34-item survey assessing barriers to career development and workplace obstacles (14 items), along with demographic/occupation characteristics (22 items), was distributed among dental researchers at the Women In Science Network meetings at 2024 AADOCR/IADR General Session (QR code) and through AADOCR/IADR discussion board (online platform). Differences in barriers and workplace obstacles were analyzed between women and men with chi-square tests; comparisons were repeated among women working within versus outside academia.
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