AI Article Synopsis

  • The supplementary data relates to a study on a novel suprachoroidal visual prosthesis implanted in sheep, assessing surgical safety, device stability, and biocompatibility.
  • Nine sheep underwent surgery with an electrically inactive retinal stimulator, monitored for up to 100 days through various imaging techniques.
  • The collected data, including images and histological analysis, serves as a reference for future research, particularly concerning active retinal stimulators and the suitability of Dorper sheep as research models.

Article Abstract

The data presented here are related and supplementary data to the research article "Implantation and long-term assessment of the stability and biocompatibility of a novel 98 channel suprachoroidal visual prosthesis in sheep" [1]. In Eggenberger et al., nine sheep of the Suffolk (N=2) and Dorper (N=7) breeds were implanted in the left eye with an electrically inactive, suprachoroidal retinal stimulator (Bionic Eye) for durations of up to 100 days. The surgical safety, implant stability and device biocompatibility were assessed. Intraocular pressure measurements, indirect and infrared ophthalmoscopy and optical coherence tomography were performed at fixed time points to evaluate the clinical effects of the surgery and device implantation. Post-mortem eye tissue collection and histology was performed to measure the effects of the intervention at the cellular level. The data, including a comprehensive collection of fundus, infrared, optical coherence tomography and histology images can be used as a reference for comparison with other research, for example, active retinal stimulators. Furthermore, these data can be used to evaluate the suitability of the sheep model, in particular Dorper sheep, for future research.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8711049PMC
http://dx.doi.org/10.1016/j.dib.2021.107634DOI Listing

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