Early Experience With Tenecteplase at a Comprehensive Stroke Center.

Neurol Clin Pract

HMH JFK University Medical Center (SP, SS, NG, LS, SM, JK), Neuroscience Institute, Edison, NJ; and Emergency Department (ID), HMH JFKUMC, Edison, NJ.

Published: December 2021

Purpose Of Review: Tenecteplase has been studied and recommended as an alternative thrombolytic agent in patients with acute stroke. A brief review of clinical trials and guidelines pertinent to our clinical decision algorithm is described. This is followed by operational steps that were made to create and implement a clinical pathway based on available evidence in which tenecteplase is used in select patients with stroke at our comprehensive stroke center.

Recent Findings: A number of patients have been treated at our center with IV tenecteplase. A case is presented to illustrate the successful implementation of this new process.

Summary: Development of our protocol is discussed in detail to enable other centers to create their own clinical pathways for thrombolytic treatment of acute ischemic stroke using tenecteplase.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8723952PMC
http://dx.doi.org/10.1212/CPJ.0000000000001096DOI Listing

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