Chemical investigation of the edible mushroom led to the isolation of one new highly degraded sterol (), and one new β-carboline alkaloid (), along with nine known compounds (-) for the first time from this mushroom. The structures of new compounds were elucidated using HR-ESI-MS data and NMR spectroscopy. In addition, anti-inflammatory activity of new compounds was evaluated against lipopolysaccharide-induced NO production in RAW 264.7 macrophages. Compound exhibited a good anti-inflammatory activity with IC value of 9.88 ± 0.48 μM, and compound exhibited a weak inhibitory effect with IC value of 71.36 ± 5.11 μM.
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| http://dx.doi.org/10.1080/14786419.2021.2023146 | DOI Listing |
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