Objective: To determine the appropriate MRI criteria for the radiological diagnosis of significant quadriceps fat pad edema, to investigate the relationship between these criteria and anterior knee pain, and to evaluate possible structural and positional factors in the etiology.
Material And Methods: In this retrospective case-control study, individuals with and without quadriceps fat pad edema in the knee MRIs taken between May 2016 and December 2018 were determined as the case and control groups, respectively, in a ratio of 1:1. The MRI criteria for significant quadriceps fat pad edema were set as 10 mm and above the anterior-posterior diameter of the quadriceps fat pad, posterior convexity, and an increased signal in the fat-suppressed proton density sequence. The groups were compared for anterior knee pain, pain characteristics, working positions (sitting and standing), and MRI findings of structural factors. P < 0.05 was considered statistically significant.
Results: A total of 108 individuals were evaluated. Anterior knee pain was more common in the case group (49/54, p < 0.001) and was highly correlated with signs of quadriceps fat pad edema (R = -0,657). Frequent pain at night (18/54, p = 0.013), increased pain when walking upstairs (40/54, p = 0.003), knees are flexed (43/54, p < 0.001), and decreased pain when knees are extended (42/54, p < 0.001) were significantly high in the case group. No significant differences were observed in working position and structural factors.
Conclusion: Quadriceps fat pad edema is significantly associated with anterior knee pain and certain specific pain characteristics.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1007/s00256-021-03980-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Relationship Between Quantitative Magnetic Resonance Imaging Measures and Functional Changes in Patients With Duchenne Muscular Dystrophy.
Muscle Nerve
December 2024
AMRA Medical AB, Linköping, Sweden.
Introduction/aims: Improved methodologies to monitor the progression of Duchenne muscular dystrophy (DMD) are needed, especially in the context of clinical trials. We report changes in muscle magnetic resonance imaging (MRI) parameters in participants with DMD, including changes in lean muscle volume (LMV), muscle fat fraction (MFF), and muscle fat infiltration (MFI) and their relationship to changes in functional parameters.
Methods: MRI data were obtained as part of a clinical study (NCT02310763) of domagrozumab, an antibody-targeting myostatin that negatively regulates skeletal muscle mass.
Clinical Implications of Functional Imaging in the Assessment of Bronchiectasis-Associated Sarcopenia.
Arch Bronconeumol
December 2024
Pulmonology Department-Muscle Wasting and Cachexia in Chronic Respiratory Diseases and Lung Cancer Research Group, IMIM-Hospital del Mar, Parc de Salut Mar, Department of Medicine and Life Sciences (MELIS), Universitat Pompeu Fabra (UPF), Barcelona Biomedical Research Park (PRBB), Dr. Aiguader, 88, E-08003 Barcelona, Spain; Centro de Investigación en Red de Enfermedades Respiratorias (CIBERES), Instituto de Salud Carlos III (ISCIII), Monforte de Lemos, 5, E-28029 Madrid, Spain. Electronic address:
Introduction: Bronchiectasis is a complex lung disease with poorly studied systemic manifestations. Patients with bronchiectasis-associated sarcopenia exhibit a specific differential profile of functional muscle phenotype (vastus lateralis, VL), which may be analyzed using imaging (ultrasound and magnetic resonance imaging, MRI).
Methods: Ultrasound and MRI were used to explore functional imaging parameters in quadriceps of 20 patients with stable bronchiectasis and 10 healthy controls.
A novel assessment of the differences in various measurements in patients with patella alta and baja: a retrospective cross-sectional study.
Quant Imaging Med Surg
December 2024
Department of Radiology, Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey.
Background: Insall-Salvati index (ISI) is widely used to evaluate patella position, the specific relationship between quadriceps patellar tendon angle (QPA) and patellofemoral measurements remains unclear. Understanding this relationship could provide valuable insights into diagnosing and treating knee pain, instability, and patellofemoral pathologies more effectively. In this study, we aimed to assess whether there was a significant difference between the patients with patella alta and baja in terms of many patellofemoral measurements and pathologies.
View Article and Find Full Text PDFReproducibility of proton density fat fraction assessment of thigh muscle in a multi-site, multi-vendor cohort study at 10 years after anterior cruciate ligament reconstruction.
Quant Imaging Med Surg
December 2024
Program for Advanced Musculoskeletal Imaging, Cleveland Clinic, Cleveland, OH, USA.
Background: Dixon-based magnetic resonance imaging (MRI) intramuscular proton density fat fraction (PDFF) is a potentially useful imaging biomarker of muscle quality. However, multi-vendor, multi-site reproducibility of intramuscular PDFF quantification, required for large clinical studies, can be strongly dependent on acquisition and processing. The purpose of this study was (I) to develop a 6-point Dixon MRI-based acquisition and processing technique for reproducible multi-vendor, multi-site quantification of thigh intramuscular PDFF; and (II) to evaluate the ability of the technique to detect differences in thigh muscle status between operated .
View Article and Find Full Text PDFExercise Training Counteracts Compromised Mitochondrial Capacity Induced by Energy Restriction in Prediabetics in a Sex-Dependent Manner.
Scand J Med Sci Sports
December 2024
Department of Nutrition, Exercise and Sports (NEXS), University of Copenhagen, Copenhagen, Denmark.
The objective of this randomized controlled trial was to examine if exercise training can counteract energy restriction-induced impairment of mitochondrial capacity in skeletal muscle of 55-70-years people with prediabetes and metabolic syndrome. The potential impact of sex was explored. Fifty sedentary men and women with prediabetes and metabolic syndrome (age: 61 ± 6 (±SD) years, BMI: 29.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!