Objective: To explore the effect of bundle management strategy in early mobility of patients with mechanical ventilation.
Methods: Seventy-two mechanically ventilated patients admitted to the respiratory intensive care unit (RICU) of Fenyang Hospital of Shanxi Province from December 2019 to June 2020 were enrolled. The patients were divided into routine nursing control group (routine control group) and early mobility bundle management group (bundle group), with 36 cases in each group. The routine control group received regular nursing, including monitoring vital signs, raising the head of the bed, turning over and buttoning the back every 2 hours, daily awakening, airway humidification, prevention of digestive tract ulcer, analgesia and sedation management, prevention of deep vein embolism, pipeline management, regular monitoring of blood gas analysis and electrolytes according to the changes of the condition, prevention of aspiration, prevention of bacterial colonization, correct hand hygiene, and so on. The bundle group implemented the cluster early mobility strategy based on routine nursing. Firstly, set up a professional team to execute the standards. The team determined the plan and implemented the 4-level mobility plan, companied with psychological intervention, decided the termination standard and quality control. The incidence of intensive care unit acquired weakness (ICU-AW), ventilator-associated pneumonia (VAP), delirium, the duration of mechanical ventilation and the length of intensive care unit (ICU) stay were evaluated.
Results: Compared with the routine control group, the incidences of ICU-AW, VAP, and delirium in the bundle group were significantly lower (the incidence of ICU-AW: 36.11% vs. 69.44%, χ = 8.025, P = 0.005; the incidence of VAP: 8.33% vs. 30.56%, χ = 5.675, P = 0.017; the incidence of delirium: 5.56% vs. 36.11%, χ = 10.180, P = 0.001), the duration of mechanical ventilation was significantly shorter (days: 7.13±1.34 vs. 10.46±1.48, t = -10.145, P < 0.001), and the length of ICU stay was also significantly decreased (days: 9.03±2.43 vs. 13.06±3.63, t = -5.535, P < 0.001).
Conclusions: The implementation of bundle management strategy of early mobility can promote the rehabilitation of mechanical ventilated patients, improve the prognosis and the quality of life. The effect is noticeable and it is worth popularizing.
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http://dx.doi.org/10.3760/cma.j.cn121430-20210802-01113 | DOI Listing |
Sci Rep
January 2025
Department of Early Prehistory and Quaternary Ecology, Institute of Prehistory, Early History and Medieval Archeology, University of Tübingen, Tübingen, Germany.
Archaeologists can use the provenance of lithic raw materials to examine the movements, territories, and settlement dynamics of hunter-gatherers. Several studies have used macroscopic analyses to propose the long-distance transport of raw material during the Gravettian and the Magdalenian of the Swabian Jura in Central Europe. Until now hypotheses about raw material transport in this region were not based on reproducible analyses.
View Article and Find Full Text PDFActa Orthop
January 2025
Department of Orthopaedic Surgery, Health Møre and Romsdal HF, Kristiansund Hospital, Kristiansund; Department of Neuromedicine and Movement Science, NTNU, Trondheim, Norway.
Background And Purpose: The optimal approach to the hip joint in patients with displaced femoral neck fractures (dFNF) receiving a total hip arthroplasty (THA) remains controversial. We compared the direct lateral approach (DLA) with the direct anterior approach (DAA) primarily on Timed Up and Go (TUG), and secondarily on the Forgotten Joint Score (FJS), the Oxford Hip Score (OHS), EQ5D-5L, and the EQ5D-VAS.
Methods: Between 2018 and 2023, we conducted a randomized controlled trial including elderly patients with dFNFs treated with THA.
Due to their self-renewal and differentiation capabilities, pluripotent stem cells hold immense potential for advancing our understanding of human disease and developing cell-based or pharmacological interventions. Realizing this potential, however, requires a thorough understanding of the basal cellular mechanisms which occur during differentiation. Lipids are critical molecules that define the morphological, biochemical, and functional role of cells.
View Article and Find Full Text PDFCureus
December 2024
Trauma and Orthopaedics, Wythenshawe Hospital, Manchester University NHS Foundation Trust, Manchester, GBR.
Introduction Achilles tendon rupture (ATR) represents a significant musculoskeletal injury that can affect many patients' mobility and quality of life. Treatment of ATR consists of both conservative and surgical options, with the traditional belief being that surgical intervention reduces the risk of re-rupture. However, with the introduction of physiotherapy-led functional rehabilitation strategies with early mobilization, it has been shown that re-rupture rates are equal among surgical and non-surgical patients.
View Article and Find Full Text PDFRSC Adv
January 2025
Institute of Porous Flow and Fluid Mechanics, Chinese Academy of Sciences Langfang Hebei 065007 China.
Supercritical CO, as an environmentally friendly and pollution-free fluid, has been applied in various EOR techniques such as CO flooding. However, the low viscosity of the gas leads to issues such as early breakthrough, viscous fingering, and gravity override in practical applications. Although effective mobility-control methods, such as CO WAG (water alternating gas)-, CO foam-, and gel-based methods, have been developed to mitigate these phenomena, they do not fundamentally solve the problem of the high gas-oil mobility ratio, which leads to reduced gas sweep efficiency.
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