Spot tests: past and present.

ChemTexts

Departament de Química Analítica, Universitat de València. Dr. Moliner, 50, Burjassot, 46100 Valencia, Spain.

Published: December 2021

AI Article Synopsis

  • Microchemistry originated in the late 18th and early 19th centuries and has evolved significantly over time.
  • Spot tests, developed in the early to mid-20th century, are key educational tools for chemistry students and have practical applications in fields like conservation, food science, forensic science, and healthcare.
  • The text aims to give a comprehensive overview of the development and current status of microchemistry and spot testing methods.

Article Abstract

Microchemistry, i.e., the chemistry performed at the scale of a microgram or less, has its roots in the late eighteenth and early nineteenth centuries. In the first half of the twentieth century a wide range of spot tests have been developed. For didactic reasons, they are still part of the curriculum of chemistry students. However, they are even highly important for applied analyses in conservation of cultural heritage, food science, forensic science, clinical and pharmacological sciences, geochemistry, and environmental sciences. Modern pregnancy tests, virus tests, etc. are the most recent examples of sophisticated spot tests. The present contribution aims to provide an overview of the past and present of this analytical methodology.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8710564PMC
http://dx.doi.org/10.1007/s40828-021-00152-zDOI Listing

Publication Analysis

Top Keywords

spot tests
12
tests microchemistry
4
microchemistry chemistry
4
chemistry performed
4
performed scale
4
scale microgram
4
microgram roots
4
roots late
4
late eighteenth
4
eighteenth early
4

Similar Publications

The biological properties of isofetamid, a new fungicide, were examined using pot tests in a greenhouse. In addition, we investigated the practical effects of isofetamid in field trials. In greenhouse pot tests, isofetamid exhibited high preventive efficacy against cucumber gray mold, powdery mildew, Corynespora leaf spot, and stem rot even at low concentrations.

View Article and Find Full Text PDF

Integration of circulating tumor DNA in biliary tract cancer: the emerging landscape.

Hepat Oncol

December 2024

Gastrointestinal Malignancies Section, Thoracic & GI Malignancies Branch, Center for Cancer Research, National Cancer Institute (NCI), National Institutes of Health, Bethesda, MD 20892, USA.

Precision medicine has emerged as a cornerstone in cancer treatment revolutionizing our approach across malignancies. Molecular profiling of biliary tract cancers (BTCs) has changed the treatment landscape positively by prolonging survival in an aggressively fatal malignancy in its advanced stages. The acquisition of tissue tumor DNA for genomic analysis in BTC is often anatomically challenging, limited by quantity and quality.

View Article and Find Full Text PDF

Background: One of the best ways to impart important skills to trainees is through simulation-based training, which is more reliable than the conventional clinical examination method. It is used in pediatric nursing training to allow nurses to practice and improve their clinical and conversational skills during an actual child encounter. A heel-prick is a complex psychomotor task that requires skill and knowledge from the pediatric nurse performing the procedure while applying for the National Newborn Screening Program.

View Article and Find Full Text PDF

Objective: Type1Screen offers islet autoantibody testing to Australians with a family history of type 1 diabetes (T1D) with the dual aims of preventing diabetic ketoacidosis (DKA) and enabling use of disease-modifying therapy. We describe screening and monitoring outcomes 2 years after implementing in-home capillary blood spot sampling.

Research Design And Methods: Data from 2,064 participants who registered between July 2022 and June 2024 were analyzed: 1,507 and 557 chose blood spot and venipuncture screening respectively.

View Article and Find Full Text PDF

Standardised activities in wheelchair rugby, comparison between athletes with coordination impairment and athletes with other impairments.

Front Sports Act Living

January 2025

Peter Harrison Centre for Disability Sport, School of Sport, Exercise, and Health Sciences, Loughborough University, Loughborough, United Kingdom.

Introduction: To determine if athletes with coordination impairment (CI) can continue playing wheelchair rugby (WR), while an evidence-based classification system, including impairment tests for CI is not yet available. This is a defensible practise if they show similar activity limitations as athletes with other eligible impairment types (OI) within the same sports class.

Methods: Standardised activities were measured in 58 elite WR athletes; 14 with CI and 44 with OI.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!