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Treatment of Radiation-Induced Brain Necrosis. | LitMetric

Treatment of Radiation-Induced Brain Necrosis.

Oxid Med Cell Longev

Department of Radiation Oncology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, No. 600, Yishan Road, Shanghai 200233, China.

Published: March 2022

Radiation-induced brain necrosis (RBN) is a serious complication of intracranial as well as skull base tumors after radiotherapy. In the past, due to the lack of effective treatment, radiation brain necrosis was considered to be progressive and irreversible. With better understanding in histopathology and neuroimaging, the occurrence and development of RBN have been gradually clarified, and new treatment methods are constantly emerging. In recent years, some scholars have tried to treat RBN with bevacizumab, nerve growth factor, and gangliosides and have achieved similar results. Some cases of brain necrosis can be repairable and reversible. We aimed to summarize the incidence, pathogenesis, and treatment of RBN.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8720020PMC
http://dx.doi.org/10.1155/2021/4793517DOI Listing

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